Molecular Motors: Rotary Mechanisms

This lecture explores the coordination of molecular motors in large-scale functions, focusing on calcium signaling triggering motor action. It delves into the mechanisms of myosin II, kinesin, dynein, and myosin V, highlighting their different binding states and velocities. The instructor discusses rotary motors, multiple motor transport in fish melanophores, and the bacterial flagellar motor, emphasizing their unique functionalities. Furthermore, the lecture covers the rotary motor function, ATP-synthase structure, and the impact of pH on motor rotation. Polymerization motors, actin's role in Listeria motility, and segregation by polymerization are also discussed, along with the forces generated by polymerization and the speed of translocation ratcheting.