This lecture covers the different categories of diuretic drugs, their main clinical uses, side effects, and mechanisms of action. It explains the main ionic transporters involved and drug interventions in the renin-angiotensin-aldosterone system. The lecture also discusses the daily water balance in the kidneys and the types of medication. Furthermore, it delves into the site of action of diuretics, the cellular types in the renal tubule, and the pharmacological characteristics of main diuretics.