Understanding Generative Models of Protein Sequences

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Protein Co-evolution Analysis

Delves into protein co-evolution analysis, covering discoveries, residue contacts, and direct coupling analysis.

Exploring Evolution: Molecular Evidence and Mechanisms

Explores molecular evidence and mechanisms of evolution, including phylogenetic trees and protein comparisons.

Exploring Evolution: Molecular Insights and Protein Comparison

Explores evolution through enzymes, DNA models, and protein comparisons, discussing molecular insights and evolutionary mechanisms.

Protein Structure Prediction: AlphaFold Evolution and OpenFold Insights

Explores the evolution of protein structure prediction with AlphaFold models and introduces OpenFold insights.

Constructing Phylogenetic Trees: UPGMA Algorithm

Covers the UPGMA algorithm for constructing phylogenetic trees and understanding genetic relationships.

Biological structure and function emerge from unsupervised learning

Delves into how biological structure and function are decoded through unsupervised learning of protein sequences.

Protein Design: Structure and Function

Covers protein design fundamentals, including secondary structures, amino acid propensity, loops, and computational methods.

Phylogenetic Tree Construction

Covers the stages of building a phylogenetic tree using DNA sequences and the UPGMA method.

Protein Interaction Fingerprinting with Geometric Deep Learning

Explores deciphering protein interaction fingerprints using geometric deep learning and the challenges in computational protein-protein interaction design.

Protein Composition and Structure

Explores protein composition, peptide bonds, secondary structures, and protein folding prediction.