This lecture covers reward-based learning in neuronal networks, focusing on the dopamine reward signal, dopaminergic innervation of the striatum, and the role of striatal projection neurons. It also discusses dopamine modulation of synaptic plasticity, the whisker detection task, and the cell-type-specific function of striatal neurons. The instructor explains dopamine learning in the whisker detection task and the mechanisms underlying reward-based learning, emphasizing the reinforcement of synaptic circuits driving goal-directed behavior.