Tuberculosis: Treatment and Drug Resistance

This lecture covers the basics of tuberculosis, a bacterial disease affecting the lungs, with symptoms like coughing, fatigue, and weight loss. It explains the importance of organic chemistry in treating tuberculosis and the use of first-line drugs like isoniazid and rifampicin. The lecture also delves into drug-resistant tuberculosis, caused by slow bacterial division and mycolic acids in the cell wall. Treatment involves second-line drugs like cycloserine and capreomycin. The session concludes with a discussion on the challenges of antibiotic resistance and the need for new treatment strategies.