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Patrick Aebischer

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Astrocyte-targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast-fatigable motor units in a mouse model of amyotrophic lateral sclerosis

The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis

Parkin functionally interacts with PGC-1 proportional to to preserve mitochondria and protect dopaminergic neurons

A subcutaneous cellular implant for passive immunization against amyloid-beta reduces brain amyloid and tau pathologies

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons

Tmc gene therapy restores auditory function in deaf mice

SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology