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Patrick Aebischer

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GDNF-secreting human neural progenitor cells increase tyrosine hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeys

Viral vectors, animal models and new therapies for Parkinson's disease

The KRAB repressor domain can trigger de novo promoter methylation during mouse early embryogenesis

Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy

GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS

Playing Defense Against Lou Gehrig's Disease

Metabolic correction in oligodendrocytes derived from metachromatic leukodystrophy mouse model by using encapsulated recombinant myoblasts

Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease

Expression of mutated huntingtin fragment in the putamen is sufficient to produce abnormal movement in non-human primates

Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation