Skip to main content

Search

Show all results for

Home

Person

Johan Jakobsson

This person is no longer with EPFL

About
Privacy
Disclaimer

Copyright © 2025 EPFL, all rights reserved

Graph Chatbot

About this result

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

KAP1 controls endogenous retroviruses in embryonic stem cells

Didier Trono, Daniel Constam, Séverine Reynard, Jacques Rougemont, Sonia Verp, Hillary Layard-Liesching, Helen Mary Rowe, Johan Jakobsson, Pierre Maillard

More than forty per cent of the mammalian genome is derived from retroelements, of which about one-quarter are endogenous retroviruses (ERVs). Some are still active, notably in mice the highly polymorphic early transposon (ETn)/MusD and intracisternal A-ty ...

Nature Publishing Group2010

KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress

Maria del Carmen Sandi Perez, Didier Trono, Maria Isabel Cordero Campana, Jean-Charles Bensadoun, Reto Bisaz, Anna Claire Groner, Johan Jakobsson

KAP1 is an essential cofactor of KRAB-zinc finger proteins, a family of vertebrate-specific epigenetic repressors of largely unknown functions encoded in the hundreds by the mouse and human genomes. Here, we report that KAP1 is expressed at high levels and ...

2008

The KRAB repressor domain can trigger de novo promoter methylation during mouse early embryogenesis

Didier Trono, Patrick Aebischer, Friedrich Beermann, Shuangqing Liao, Johan Jakobsson

The Krüppel-associated box (KRAB) domain is a transcriptional repression module responsible for the DNA binding-dependent gene silencing activity of hundreds of vertebrate zinc finger proteins. We previously exploited KRAB-mediated repression within the co ...

2007