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Matthieu Philippe Emmanuel Zellweger

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Related publications (47)

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The outcome of light-based therapeutic approaches depends on light propagation in biological tissues, which is governed by their optical properties. The objective of this study was to quantify optical properties of brain tissue in vivo and postmortem and a ...

Spie-Soc Photo-Optical Instrumentation Engineers2015

Red and NIR light dosimetry in the human deep brain

Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Blaise Lovisa

Photobiomodulation (PBM) appears promising to treat the hallmarks of Parkinson's Disease (PD) in cellular or animal models. We measured light propagation in different areas of PD-relevant deep brain tissue during transcranial, transsphenoidal illumination ...

Iop Publishing Ltd2015

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Photobiomodulation (PBM) is a promising approach to treat Parkinson's disease (PD) symptoms in cellular or animal models. Unfortunately, little information is available on the optical parameters playing a role in the light dosimetry during PBM. We conducte ...

Spie-Int Soc Optical Engineering2015

In vivo measurement of tissue oxygenation by time-resolved luminescence spectroscopy: advantageous properties of dichlorotris(1, 10-phenanthroline)-ruthenium(II) hydrate

Hubert van den Bergh, Georges Wagnières, Patrycja Nowak-Sliwinska, Matthieu Philippe Emmanuel Zellweger, Veronika Huntosova, Sandrine Gay, Senthil Kumar Rajendran

Measuring tissue oxygenation in vivo is of interest in fundamental biological as well as medical applications. One minimally invasive approach to assess the oxygen partial pressure in tissue (pO(2)) is to measure the oxygen-dependent luminescence lifetime ...

Spie-Soc Photo-Optical Instrumentation Engineers2014

Optical spectroscopy of the bladder washout fluid to optimize fluorescence cystoscopy with Hexvix

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Blaise Lovisa, Carla Martoccia

Fluorescence cystoscopy enhances detection of early bladder cancer. Water used to inflate the bladder during the procedure rapidly contains urine, which may contain fluorochromes. This frequently degrades fluorescence images. Samples of bladder washout flu ...

Spie-Soc Photo-Optical Instrumentation Engineers2014

Study of the stability of the 5-aminolevulinic acid tyrosine ester in aqueous solution

Qian Wang, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Sandrine Gay, Carla Martoccia

Photodynamic therapy based on photoactivable porphyrins (PAPs) can treat various dermatological conditions. The side-effects as well as the non-selective or insufficient accumulation of PAPs in the targeted tissues limit performances. We studied the stabil ...

2014

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Summary Background Photodynamic therapy (PDT) with precursors of photoactivable porphyrins is a well-established treatment modality for skin pathologies as well as hair removal. Pain is a major side effect thereof, and it affects the treatment compliance a ...

Elsevier2013

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Background: Photodynamic therapy (PDT) with Metvix® is a good therapeutic option to treat actinic keratosis, but it presents drawbacks (pain, lesion recurrences, heterogeneous outcome), emphasizing the possible need to individualize treatment. Objective: W ...

Karger2013

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The hydrodynamic rebalancing laser (HRL) procedure is an ophthalmic therapy based on the administration of subthreshold infrared (810 nm) laser light to selected areas on the retina to treat various retina diseases. Heterogeneities of tissue response are o ...

Spie-Soc Photo-Optical Instrumentation Engineers2012

Assessment of a sheep animal model to optimize photodynamic therapy with Foscan in the esophague

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, François André Borle

Precursor lesions of oesophagus adenocarcinoma constitute a clinical dilemma. Photodynamic therapy (PDT) is an effective treatment for this indication, but it is difficult to optimise without an appropriate animal model. For this reason, we assessed the sh ...

Wiley-Blackwell2009