Publications by Adrian Bachmann

Optical apparatus for dual beam heterodyne Fourier domain optical coherence tomography, has detector that synchronizes phase shift such that sample signal or sample interface moving at arbitrary velocity is detected by phase change

Theo Lasser, Rainer Leitgeb, Martin Villiger, Adrian Bachmann, Roland Michaely

NOVELTY - The apparatus has an optical unit for splitting a source field to produce and combine reference and biomedical sample light fields. An optical and electronic unit records a spectral interference pattern between combined light fields. A controlled ...

2008

Frequency encoded assessment of retinal physiology

Theo Lasser, Adrian Bachmann, Rainer Leitgeb, Roland Michaely, Cédric Blatter

We demonstrate in-vivo functional imaging of the human retina with Fourier domain optical coherence tomography employing frequency encoding of an excitation pattern. The principle is based on projecting a modulated rectangular pattern across the foveal reg ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2008

Vectorial retinal blood flow and optical vessel vivisection for 3D angiography with high resolution resonant Doppler OCT

Theo Lasser, Martin Villiger, Rainer Leitgeb, Cédric Blatter, Adrian Bachmann, Roland Michaely

PURPOSE: To perform high speed and completely non-invasive 3D angiography at the optic nerve head region and to reconstruct vectorial 3D blood flow from optically segmented blood vessel structure as a pre-requisite for testing retinal function and physiolo ...

2007

Intensity based quantification of fast retinal blood flow in 3D via high resolution resonant Doppler spectral OCT

Theo Lasser, Cédric Blatter, Rainer Leitgeb, Martin Villiger, Adrian Bachmann, Roland Michaely

Resonant Doppler Fourier Domain Optical Coherence Tomography is a functional imaging modality for quantifying fast tissue flow. The method profits from the effect of interference fringe blurring in spectrometer-based FDOCT in the presence of sample motion. ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2007

Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography

Theo Lasser, Cédric Blatter, Rainer Leitgeb, Martin Villiger, Adrian Bachmann, Roland Michaely

Resonant Doppler Fourier domain optical coherence tomography (FDOCT) is a functional imaging tool for extracting tissue flow. The method is based on the effect of interference fringe blurring in spectrometer-based FDOCT, where the path difference between s ...

SPIE Society of Photo-optical Instrumentation Engineers2007

Resonant Doppler flow imaging and optical vivisection of retinal blood vessels

Theo Lasser, Cédric Blatter, Rainer Leitgeb, Martin Villiger, Adrian Bachmann

For Fourier domain optical coherence tomography any sample movement during camera integration causes blurring of interference fringes and as such reduction of sensitivity for flow detection. The proposed method overcomes this problem by phase-matching a re ...

2007

Dual-beam heterodyne Fourier domain optical coherence tomography

Theo Lasser, Rainer Leitgeb, Adrian Bachmann, Roland Michaely

We report on a novel method combining achromatic complex FDOCT signal reconstruction with a common path and dual beam configuration. The complex signal reconstruction allows resolving the complex ambiguity of the Fourier transform and to enhance the achiev ...

2007

Optical imaging apparatus for sample imaging method e.g. in-vivo measurement of full three-dimensional tissue volume has at least one detector that detects resulting spectral interference pattern at exit of interferometer

Theo Lasser, Martin Villiger, Rainer Leitgeb, Adrian Bachmann, Lukas Steinmann

The invention concerns an optical imaging apparatus comprising (o) a light source (1) , (p) sample holding means, (q) an interferometer, (r) reference means, (s) an objective (8) which is adapted to have its sample side focal plane crossing a sample held i ...

2007

Phase-locked Fourier domain optical coherence tomography

Adrian Bachmann

Fourier or spectral domain optical coherence tomography (FDOCT) is a multi-dimensional interferometric imaging modality that has attracted increasing interest during the last few years. The reason is its outstanding sensitivity allowing high speed 2D and 3 ...

EPFL2007

Heterodyne Fourier domain optical coherence tomography for full range probing with high axial resolution

Theo Lasser, Rainer Leitgeb, Adrian Bachmann

One of the main drawbacks of Fourier domain optical coherence tomography (FDOCT) is the limited measurement depth range. Phase shifting techniques allow reconstructing the complex sample signal resulting in a doubled depth range. In current complex FDOCT r ...

2006