Publications by Neil Joye | EPFL Graph Search

Amplitude modulation based readout for very dense active microelectrode arrays

Alexandre Schmid, Yusuf Leblebici, Neil Joye

A readout method which is suitable for high-density active microelectrode arrays used in electrophysiology experiments is presented. Amplitude modulation of consecutive channels enables simultaneous recording and transmission of the signals recorded on mul ...

2011

Very High Density Microelectrode Array with Monolithically Integrated Readout Circuits

Alexandre Schmid, Yusuf Leblebici, Neil Joye, Sedigheh Hashemi

This paper presents the hardware realization and modeling of high-density microelectrode arrays including both microelectronic readout amplifiers as well as three-dimensional microelectrodes forming a fully integrated CMOS compatible system enabling resear ...

2010

Neuro-Electronic Interfacing Methods for High-Density CMOS-Compatible Microelectrode Arrays

Neil Joye

Recently, CMOS-based microelectrode arrays containing a high-density of electrodes have emerged as a tool enabling recording the extracellular neural electrical activity of cell cultures at subcellular resolution. However, several improvements in areas suc ...

EPFL2010

AM Modulation-based CMOS Readout Circuit for High-density Microelectrode Arrays

Alexandre Schmid, Yusuf Leblebici, Neil Joye

An innovative readout channel, based on analog amplitude modulation (AM) of the signals recorded by each electrode, is developed for high-density CMOS-based MEAs. This new readout method enables the design of a low-noise amplification stage while still rea ...

2010

Delta Compression of Neural Recordings for High-density CMOS-based Microelectrode Arrays

Alexandre Schmid, Yusuf Leblebici, Neil Joye, Michelangelo Carrozzo

Recent high-density CMOS-based MEAs contain thousands of electrodes. Hence, an off-chip acquisition system performing data compression prior to visualization and analysis on a computer is required in order to handle the large amount of data generated by ac ...

2010

Extracellular recording system based on amplitude modulation for CMOS microelectrode arrays

Alexandre Schmid, Yusuf Leblebici, Neil Joye

An innovative readout channel, based on analog amplitude modulation of the signals recorded by each sensing site, is developed for high-density CMOS-based microelectrode arrays. A single amplification stage simultaneously records the neural activity acquir ...

2010

A cell-electrode interface noise model for high-density microelectrode arrays

Alexandre Schmid, Yusuf Leblebici, Neil Joye

A cell-electrode interface noise model is developed which is dedicated to enable the co-simulation of the cell-electrode electrical characteristics, along with the electronics of novel CMOS-based MEA. The electrode noise is investigated for Pt and Pt black ...

IEEE2009

Matrice de micro électrodes à haute résolution spatiale pour la mesure du potentiel extracellulaire des cellules nerveuses

Alexandre Schmid, Yusuf Leblebici, Neil Joye

Une nouvelle approche basée sur des électrodes en 3D a été développée afin d’accroître le couplage électrique entre les cellules nerveuses et les capteurs d’une matrice de micro électrodes (MEA). Cette amélioration du couplage électrique obtenue par des ma ...

2009

Electrical modeling of the cell-electrode interface for recording neural activity from high-density microelectrode arrays

Alexandre Schmid, Yusuf Leblebici, Neil Joye

Accurate electrical models are needed to support the design of modern microelectrode arrays. The point-contact model is presented thoroughly, and an area-contact model is analytically derived in order to model the electrical characteristics of the cell-ele ...

2009

Three-Dimensional Silicon-based MEA with High Spatial Resolution

Alexandre Schmid, Yusuf Leblebici, Neil Joye

A new approach based on three-dimensional tip electrodes has been developed as a way to increase the electrical oupling between the neural cells and the individual sensors in a microelectrode array (MEA). With respect to standard planar electrodes, the ele ...

2008