Person

Vishakha Raina

Related publications (7)

Biochemistry of Microbial Degradation of Hexachlorocyclohexane and Prospects for Bioremediation

Lindane, the gamma-isomer of hexachlorocyclohexane (HCH), is a potent insecticide. Purified lindane or unpurified mixtures of this and alpha-, beta-, and gamma- isomers of HCH were widely used as commercial insecticides in the last half of the 20th century ...

2010

Enhanced biodegradation of hexachlorocyclohexane (HCH) in contaminated soils via inoculation with Sphingobium indicum B90A

Christof Holliger, Vishakha Raina

Abstract Soil pollution with hexachlorocyclohexane (HCH) has caused serious environmental problems. Here we describe the targeted degradation of all HCH isomers by applying the aerobic bacterium Sphingobium indicum B90A. In particular, we examined possibil ...

2008

New Metabolites in the Degradation of α- and γ-Hexachlorocyclohexane (HCH): Pentachlorocyclohexenes Are Hydroxylated to Cyclohexenols and Cyclohexenediols by the Haloalkane Dehalogenase LinB from Sphingobium indicum B90A

Christof Holliger, Thomas Geiger, Vishakha Raina

Technical hexachlorocyclohexane (HCH) and lindane are obsolete pesticides whose former production and use led to widespread contaminations posing serious and lasting health and environmental risks. Out of nine possible stereoisomers, α-, β-, γ-, and δ-HCH ...

American Chemical Society2008

Hydroxylated Metabolites of β- and δ-Hexachlorocyclohexane: Bacterial Formation, Stereochemical Configuration, and Occurrence in Groundwater at a Former Production Site

Christof Holliger, Vishakha Raina

Estrogenic substances discharged from wastewater treatment plants have been detected in surface sediments of receiving waters, but little is known of their vertical migration through buried sediments and their potential to contaminate subsurface waters. Th ...

2007

Haloalkane Dehalogenase LinB is responsible for β- and δ-hexachlorocyclohexane transoformation in sphingobium indicum B90A

Christof Holliger, Vishakha Raina

Incubation of resting cells of Sphingobium indicum B90A, Sphingobium japonicum UT26, and Sphingobium francense Sp+ showed that they were able to transform ß- and -hexachlorocyclohexane (ß- and -HCH, respectively), the most recalcitrant hexachlorocyclohexan ...

2006

Enantioselective transformation of α-hexachlorocyclohexane by the dehydrochlorinases LinA1 and LinA2 from the soil bacterium Sphingomonas paucimobilis B90A

Christof Holliger, Vishakha Raina

Sphingomonas paucimobilis B90A contains two variants, LinA1 and LinA2, of a dehydrochlorinase that catalyzes the first and second steps in the metabolism of hexachlorocyclohexanes (R. Kumari, S. Subudhi, M. Suar, G. Dhingra, V. Raina, C. Dogra, S. Lal, J. ...

2005

Organization of lin genes and IS6100 among different strains of hexachlorocyclohexane-degrading Sphingomonas paucimobilis: Evidence for horizontal gene transfer

Christof Holliger, Vishakha Raina

The organization of lin genes and IS6100 was studied in three strains of Sphingomonas paucimobilis (1390A, Sp+, and UT26) which degraded hexachlorocyclohexane (HCH) isomers but which had been isolated at different geographical locations. DNA-DNA hybridizat ...

2004

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