Publications by Steve Comby | EPFL Graph Search

Luminescent Lanthanide Helicates Self-Assembled from Ditopic Ligands Bearing Phosphonic Acid or Phosphoester Units

Jean-Claude Bünzli, Anne-Sophie Chauvin, Steve Comby, Cyntia De Piano, Céline Rita Duhot, Matthias Baud

A series of hexadentate ditopic receptors incorporating benzimidazole moieties have been designed, which are fitted with phosphonic acid or phosphoethylester coordinating units. In addition, poly(oxyethylene) pendants have been introduced on the benzimidaz ...

2009

Luminescent lanthanides bioprobes emitting in the visible and/or near-infrared ranges

Steve Comby

This Ph.D. work deals with the development of lanthanide-based bioprobes for biomedical analyses and imaging. For this purpose, two different approaches have been followed, one focusing on visible-emitting complexes, while the second addresses the sensitiz ...

EPFL2008

A Versatile Ditopic Ligand System for Sensitizing the Luminescence of Bimetallic Lanthanide Bio-Imaging Probes

Jean-Claude Bünzli, Anne-Sophie Chauvin, Caroline Vandevyver, Bo Song, Steve Comby

The homoditopic ligand 6,6’- [methylenebis(1-methyl-1H-benzimid- azole-5,2-diyl)]bis(4-{2-[2-(2-methoxy- ethoxy)ethoxy]ethoxy}pyridine-2-carboxylic acid) (H2LC2) has been tailored to self-assemble with lanthanide ions (LnIII), which results in the formatio ...

2008

Lanthanide Bimetallic Helicates for in Vitro Imaging and Sensing

Jean-Claude Bünzli, Anne-Sophie Chauvin, Caroline Vandevyver, Bo Song, Steve Comby

As the need for targeting luminescent biolabels increases, for mapping selected analytes, imaging of cells and organs, and tracking in cellulo processes, lanthanide bimetallic helicates are emerging as versatile bioprobes. The wrapping of three ligand stra ...

2008

A Polyoxyethylene-Substituted Bimetallic Europium Helicate for Luminescent Staining of Living Cells

Jean-Claude Bünzli, Anne-Sophie Chauvin, Caroline Vandevyver, Bo Song, Steve Comby

The homoditopic ligand

H_2L^{C3}

has been designed to form neutral triple-stranded bimetallic helicates of overall composition [

Ln_2(L^{C3})_3

]. The grafting of the polyoxyethylene fragments ensures water solubility and also favors cell penetration whi ...

2007

New Opportunities for Lanthanide Luminescence

Jean-Claude Bünzli, Anne-Sophie Chauvin, Caroline Vandevyver, Steve Comby

Trivalent lanthanide ions display fascinating optical properties. The discovery of the corresponding elements and their fist industrial uses were intimately linked to their optical properties. This relationship has been kept alive until today when many hig ...

2007

Luminescent lanthanide bimetallic triple-stranded helicates as potential cellular imaging probes

Jean-Claude Bünzli, Anne-Sophie Chauvin, Caroline Vandevyver, Steve Comby

Water-soluble triple-stranded [Ln2(L)3] helicates have been successfully tested as imaging probes in human cervical adenocarcinoma cells (HeLa), the complex being not toxic and clearly staining their cytoplasm in a concentrationdependent manner. ...

2007

Stable 8-hydroxyquinolinate-based podates as efficient sensitizers of lanthanide near-infrared luminescence

Jean-Claude Bünzli, Anne-Sophie Chauvin, Steve Comby

New polydentate ligands (e.g., Tsox and TsoxMe) have been synthesized to take advantage of the chelating effect of bidentate 8-hydroxyquinolinate subunits connected to a N,N,N¢,N¢-tetraaminopropyl-1,2-ethylenediamine framework and with the aim of sensitizi ...

2006

Dual Emission from Luminescent Nonalanthanide Clusters

Rosario Scopelliti, Jean-Claude Bünzli, Steve Comby

Clusters containing nine lanthanide and six sodium ions are crystallized with the help of a tridentate ligand bearing a phosphonic acid group; the structure of the EuIII compound reveals a host-guest assembly Eu⊂Na6Eu8L16 with a substantial quantum yield ( ...

2006

Lanthanide 8-hydroxyquinoline-based podates with efficient emission in the NIR range

Anne-Sophie Chauvin, Steve Comby

The novel hydroxyquinoline-containing tetrapodal ligand forms water soluble and stable chelates and is a good sensitizer of the NIR luminescence of its NdIII and YbIII complexes; its easy synthesis opens the way for potential biomedical applications. ...

2005

Steve Comby

Graph Chatbot

Chat with Graph Search

Luminescent Lanthanide Helicates Self-Assembled from Ditopic Ligands Bearing Phosphonic Acid or Phosphoester Units

Luminescent lanthanides bioprobes emitting in the visible and/or near-infrared ranges

A Versatile Ditopic Ligand System for Sensitizing the Luminescence of Bimetallic Lanthanide Bio-Imaging Probes

Lanthanide Bimetallic Helicates for in Vitro Imaging and Sensing

A Polyoxyethylene-Substituted Bimetallic Europium Helicate for Luminescent Staining of Living Cells

New Opportunities for Lanthanide Luminescence

Luminescent lanthanide bimetallic triple-stranded helicates as potential cellular imaging probes

Stable 8-hydroxyquinolinate-based podates as efficient sensitizers of lanthanide near-infrared luminescence

Dual Emission from Luminescent Nonalanthanide Clusters

Lanthanide 8-hydroxyquinoline-based podates with efficient emission in the NIR range

A Versatile Ditopic Ligand System for Sensitizing the Luminescence of Bimetallic Lanthanide Bio-Imaging Probes

Luminescent lanthanides bioprobes emitting in the visible and/or near-infrared ranges

Luminescent Lanthanide Helicates Self-Assembled from Ditopic Ligands Bearing Phosphonic Acid or Phosphoester Units

Dual Emission from Luminescent Nonalanthanide Clusters

New Opportunities for Lanthanide Luminescence

Stable 8-hydroxyquinolinate-based podates as efficient sensitizers of lanthanide near-infrared luminescence

Lanthanide 8-hydroxyquinoline-based podates with efficient emission in the NIR range

Luminescent lanthanide bimetallic triple-stranded helicates as potential cellular imaging probes

Lanthanide Bimetallic Helicates for in Vitro Imaging and Sensing

A Polyoxyethylene-Substituted Bimetallic Europium Helicate for Luminescent Staining of Living Cells