Person

Benedikt Steitz

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Related publications (17)

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Magnetic, paramagnetic and/or superparamagnetic nanoparticles

Heinrich Hofmann, Jatuporn Salaklang, Alke Fink, Benedikt Steitz, Andrija Finka

The present invention relates to nanoparticles having a mean diameter of < 500nm and comprising, at their surface, a selected material. The nanoparticles are taken up by cells under physiological conditions and can be used to isolate interaction partners o ...

2009

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Primary cell lines are more difficult to transfect when compared to immortalized/transformed cell lines, and hence new techniques are required to enhance the transfection efficiency in these cells. We isolated and established primary cultures of synoviocyt ...

2008

Optical properties of annealed Mn2+-doped ZnS nanoparticles

Heinrich Hofmann, Alke Fink, Benedikt Steitz, Yvonne Axmann

Cysteine stabilized ZnS and Mn2+-doped ZnS nanoparticles were synthesized by a wet chemical route. Using the ZnS:Mn2+ nanoparticles as seeds, silica-coated ZnS (ZnS@Si) and ZnS:Mn2+ (ZnS:Mn2+@Si) nanocomposites were formed in water by hydrolysis and conden ...

2008

Dielectrophoresis-based particle exchanger for the manipulation and surface functionalization of particles

Philippe Renaud, Heinrich Hofmann, Jeffrey Alan Hubbell, Thomas Michael Braschler, Nicolas Demierre, Benedikt Steitz, Raphaël Tornay, Andrija Finka

We present a microfluidic device where micro- and nanoparticles can be continuously functionalized in flow. This device relies on an element called particle exchanger, which allows for particles to be taken from one medium and exposed to some reagent while ...

2008

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The influence of the composition of the polymer coated polyvinyl alcohol (PVA), vinyl alcohol/vinyl amine copolymer (A-PVA) and polyethylenimine (PEI) coated superparamagnetic iron oxide nanoparticles (SPIONs) on the colloidal stability, cytotoxicity and c ...

2008

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Recently, functionalized superparamagnetic iron oxide nanoparticles (SPIONs) have been utilized for protein separation and therapeutic delivery of DNA and drugs. The development of new methods and tools for the targeting and identification of specific biom ...

Wiley-Blackwell2008

Characterization of PEI-coated superparamagnetic iron oxide nanoparticles for transfection: Size distribution, colloidal properties and DNA interaction

Heinrich Hofmann, Alke Fink, Benedikt Steitz

Superparamagnetic iron oxide nanoparticles (SPIONs) were coated with polyethylenimine. Here, we briefly describe the synthesis as well as DNA:PEI:SPION complexes and the characterization of the compounds according to their particle size, zeta-potential, mo ...

2007

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The functionalization of nanoparticles is conditio sine qua non in studies of specific interaction with a biological target. Often, their biological functionality is achieved by covalent binding of bioactive molecules on a preexisting single surface coatin ...

2007

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The invention relates to superparamagnetic iron oxide nanoparticles for use in sutureless thermal mediated tissue fusion. The nanoparticles are dispersed in a biocompatible solder material and heated by application of an alternating electromagnetic field. ...

2007

PRODUCTION AND BIOFUNCTIONALIZATION OF MAGNETIC NANOBEADS FOR MAGNETIC SEPARATION OF MESSENGER RNA

Heinrich Hofmann, Alke Fink, Benedikt Steitz

The synthesis of nanosized beads of superparamagnetic iron oxide nanoparticles coated with 3-(aminopropyl)triethoxysilane is reported in this paper. The resulting beads are agglomerates of SPIONs with an open fractal like structure. These beads have been e ...

2007