Publications by Miguel Nicolelis

Creating a neuroprosthesis for active tactile exploration of textures

Intracortical microstimulation (ICMS) of the primary somatosensory cortex (S1) can produce percepts that mimic somatic sensation and, thus, has potential as an approach to sensorize prosthetic limbs. However, it is not known whether ICMS could recreate act ...

National Academy of Sciences2019

Non-invasive, Brain-controlled Functional Electrical Stimulation for Locomotion Rehabilitation in Individuals with Paraplegia

Mohamed Bouri, Solaiman Shokur, Miguel Nicolelis

Spinal cord injury (SCI) impairs the flow of sensory and motor signals between the brain and the areas of the body located below the lesion level. Here, we describe a neurorehabilitation setup combining several approaches that were shown to have a positive ...

Nature Research2019

EXiO-A Brain-Controlled Lower Limb Exoskeleton for Rhesus Macaques

Hannes Bleuler, Mohamed Bouri, Jeremy Olivier, Miguel Nicolelis, Tristan Hubert Vouga

Recent advances in the field of brain-machine interfaces (BMIs) have demonstrated enormous potential to shape the future of rehabilitation and prosthetic devices. Here, a lower-limb exoskeleton controlled by the intracortical activity of an awake behaving ...

Ieee-Inst Electrical Electronics Engineers Inc2017

Grand Challenges for Global Brain Sciences

Sean Lewis Hill, Miguel Nicolelis, Corrado Cali

The next grand challenges for society and science are in the brain sciences. A collection of 60+ scientists from around the world, together with 10+ observers from national, private, and foundations, spent two days together discussing the top challenges th ...

2016

Expanding the primate body schema in sensorimotor cortex by virtual touches of an avatar

Hannes Bleuler, Miguel Nicolelis, Solaiman Shokur

The brain representation of the body, called the body schema, is susceptible to plasticity. For instance, subjects experiencing a rubber hand illusion develop a sense of ownership of a mannequin hand when they view it being touched while tactile stimuli ar ...

National Academy of Sciences2013

A Brain-Machine Interface Enables Bimanual Arm Movements in Monkeys

Solaiman Shokur, Miguel Nicolelis, Zheng Li

Brain-machine interfaces (BMIs) are artificial systems that aim to restore sensation and movement to paralyzed patients. So far, BMIs have enabled only one arm to be moved at a time. Control of bimanual arm movements remains a major challenge. We have deve ...

Amer Assoc Advancement Science2013

Toward a whole-body neuroprosthetic

Miguel Nicolelis

Brain-machine interfaces (BMIs) hold promise for the restoration of body mobility in patients suffering from devastating motor deficits caused by brain injury, neurological diseases, and limb loss. Considerable progress has been achieved in BMIs that enact ...

Elsevier Science Bv2011

Spinal Cord Stimulation Restores Locomotion in Animal Models of Parkinson's Disease

Miguel Nicolelis

Dopamine replacement therapy is useful for treating motor symptoms in the early phase of Parkinson's disease, but it is less effective in the long term. Electrical deep-brain stimulation is a valuable complement to pharmacological treatment but involves a ...

American Association for the Advancement of Science2009

Gait pattern prediction via bilateral neural ensemble recordings in motor cortex in rats

Hannes Bleuler, Solaiman Shokur, Miguel Nicolelis

We are interested in developing and building an experimental system for controlling a quadruped robot with a brain-derived signal of a rat. We recorded large ensembles of neurones in left M1 and right M1 and S1 using chronically implanted multi-electrodes ...

Fens2008