Person
Andrea Zaffalon
This person is no longer with EPFL
Related publications (6)
Methods of derivation and/or propagation of epithelial cells
Yann Barrandon, Andrea Zaffalon
The present invention relates to methods of derivation and/or propagation of epithelial cells from tissue comprising culturing said tissue in media containing an effective amount of a proprotein convertase inhibitor for a period of time allowing the deriva ...
2018Capturing epidermal stemness
Regenerative medicine aims to replace or regenerate tissues or organs to re-establish their normal function. In 1975, Rheinwald and Green developed a technique to isolate and amplify epidermal stem cells. Their discovery led to the development of cultured ...
EPFL2016A single epidermal stem cell strategy for safe ex vivo gene therapy
Graham Knott, Jacques Rougemont, Yann Barrandon, Ariane Rochat, Andrea Zaffalon, Nicolas Grasset, Stéphanie Danièle Hélène Droz-Georget, Sara Benmohammed, Emmanuelle Savioz-Dayer, Alessandra Recchia
There is a widespread agreement from patient and professional organisations alike that the safety of stem cell therapeutics is of paramount importance, particularly for ex vivo autologous gene therapy. Yet current technology makes it difficult to thoroughl ...
Wiley Open Access2015LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis
Yann Barrandon, Andrea Zaffalon
Corneal integrity and transparency are indispensable for good vision. Cornea homeostasis is entirely dependent upon corneal stem cells, which are required for complex wound-healing processes that restore corneal integrity following epithelial damage. Here, ...
American Society for Clinical Investigation2014Capturing epidermal stemness for regenerative medicine
Yann Barrandon, Ariane Rochat, François Gorostidi, Stéphanie Claudinot, Andrea Zaffalon, Nicolas Grasset, Stéphanie Danièle Hélène Droz-Georget
The skin is privileged because several skin-derived stem cells (epithelial stem cells from epidermis and its appendages, mesenchymal stem cells from dermis and subcutis, melanocyte stem cells) can be efficiently captured for therapeutic use. Main indicatio ...
Academic Press Ltd- Elsevier Science Ltd2012The functional analysis of Lrig1 in the mouse cornea
Regenerative medicine aims to recreate functional tissues in vitro for the regeneration of damaged organs and solve the dramatic problem of transplant rejection. Cornea integrity is primordial for our vision. Several therapies to regenerate healthy corneal ...
2011