Person
Sonia Verp
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Related publications (16)
Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.
DUX is a non-essential synchronizer of zygotic genome activation
Didier Trono, Sonia Verp, Sandra Eloise Kjeldsen, Delphine Yvette L Grun, Alberto De Iaco
Some of the earliest transcripts produced in fertilized human and mouse oocytes code for DUX, a double homeodomain protein that promotes embryonic genome activation (EGA). Deleting Dux by genome editing at the 1- to 2-cell stage in the mouse impairs EGA an ...
2019DUX-family transcription factors regulate zygotic genome activation in placental mammals
Didier Trono, Evaristo Jose Planet Letschert, Julien Léonard Duc, Sonia Verp, Andrea Coluccio, Alberto De Iaco
In animal embryos, transcription is mostly silent for several cell divisions, until the release of the first major wave of embryonic transcripts through so-called zygotic genome activation (ZGA). Maternally provided ZGA-triggering factors have been identif ...
2017De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET
Didier Trono, Sonia Verp, Marc Samuel Friedli, Sandra Eloise Kjeldsen, Helen Mary Rowe
Endogenous retroviruses (ERVs) undergo de novo DNA methylation during the first few days of mammalian embryogenesis, although the factors that control the targeting of this process are largely unknown. We asked whether KAP1 (KRAB-associated protein 1) is i ...
Company Of Biologists Ltd2013