Person
Lee Ann Laurent-Applegate
Related publications (8)
Depth-dependent mechanical properties of human articular cartilage obtained by indentation measurements
Pierre-Etienne Bourban, Lee Ann Laurent-Applegate, Robin Martin, Matteo Gregorio Modesto Marascio, Jens Antons
Emerging 3D printing technology permits innovative approaches to manufacture cartilage scaffolds associated with layer-by-layer mechanical property adaptation. However, information about gradients of mechanical properties in human articular cartilage is li ...
2018Human bone progenitor cells for clinical application: what kind of immune reaction does fetal xenograft tissue trigger in immuno-competent rats?
Dominique Pioletti, Lee Ann Laurent-Applegate, Tanja Cloé Hausherr
The potential of human fetal bone cells for successful bone regeneration has been shown in vivo. In particular, it has been demonstrated that the seeding of these cells in porous poly-(L-lactic acid)/ ß-tricalcium phosphate scaffolds improved the bone form ...
Cognizant Communication Corp2017Stability enhancement using hyaluronic acid gels for delivery of human fetal progenitor tenocytes
Dominique Pioletti, Alain Farron, Corinne Scaletta, Lee Ann Laurent-Applegate, Anthony Grognuz
Tendon afflictions are very common, and their negative impact is high both at the workplace and in leisure activities. Tendinopathies are increasing in prevalence and can lead to tendon ruptures, where healing is a long process with outcomes that are often ...
2016Osteogenesis imperfecta: from diagnosis and multidisciplinary treatment to future perspectives
Dominique Pioletti, Lee Ann Laurent-Applegate
Osteogenesis imperfecta is an inherited connective tissue disorder with wide phenotypic and molecular heterogen- eity. A common issue associated with the molecular ab- normality is a disturbance in bone matrix synthesis and homeostasis inducing bone fragil ...
Swiss Medical Publishers Ltd / EMH Swiss Medical Publishers2016Biologicals and fetal cell therapy for wound healing and scar management
Dominique Pioletti, Corinne Scaletta, Nathalie Hirt-Burri, Lee Ann Laurent-Applegate
Few biopharmaceutical preparations developed from biologicals are available for tissue regeneration and scar management. When developing biological treatments with cellular therapy, selection of cell types and establishment of consistent cell banks are cru ...
2011Biomechanical Evaluation of Human Skin on Various Anatomical Sites (Semester Project)
Lee Ann Laurent-Applegate, Salim Elias Darwiche
Measures of skin elasticity, immediate retraction and distention as well as pigmentation and erythema will be conducted on various anatomical sites to compile a profile of skin properties. ...
2010In vitro characterization of immune-related properties of human fetal bone cells for potential tissue engineering applications
Dominique Pioletti, Corinne Scaletta, Lee Ann Laurent-Applegate
We describe herein some immunological properties of human fetal bone cells recently tested for bone tissue engineering applications. Adult mesenchymal stem cells and adult osteoblasts were included in the study for comparison. Surface markers involved in b ...
2009Repair of critical size defects in the rat cranium using ceramic-reinforced PLA scaffolds obtained by supercritical gas foaming
Dominique Pioletti, Pierre-Etienne Bourban, Lee Ann Laurent-Applegate
Bioresorbable scaffolds made Of poly(L-lactic acid) (PLA) obtained by supercritical gas foaming were recently described as suitable for tissue engineering, portraying biocompatibility with primary osteoblasts in vitro and interesting mechanical properties ...
2007