Publications by Matthew Gibson

A minimalistic cyclic ice-binding peptide from phage display

Harm-Anton Klok, Luciano Andres Abriata, Corey Alfred Stevens, Matthew Gibson, Xudong Kong

Developing molecules that emulate the properties of naturally occurring ice-binding proteins (IBPs) is a daunting challenge. Rather than relying on the (limited) existing structure–property relationships that have been established for IBPs, here we report ...

2021

Impact of polymer-modified gold nanoparticles on brain endothelial cells: exclusion of endoplasmic reticulum stress as a potential risk factor

Harm-Anton Klok, Matthew Gibson

A library of polymer-coated gold nanoparticles (AuNPs) differing in size and surface modifications was examined for uptake and induction of cellular stress responses in the endoplasmic reticulum (ER stress) in human brain endothelial cells (hCMEC/D3). ER s ...

Informa Healthcare2016

Selective detection of epimeric pentose saccharides at physiological pH using a fluorescent receptor

Matthew Gibson, Joao Pedro De Almeida Neres, Elizabeth Fullam

Epimerisation between ribofuranose and arabinofuranose sugars is crucial in several biosynthetic pathways, but is typically challenging to monitor. Here, we have screened for fluorescent boronic acids that can be used as molecular probes for the specific d ...

Elsevier Sci Ltd2014

Personalising speech-to-speech translation: Unsupervised cross-lingual speaker adaptation for HMM-based speech synthesis

John David Scott Dines, Hui Liang, Lakshmi Babu Saheer, Matthew Gibson, Simon King

In this paper we present results of unsupervised cross-lingual speaker adaptation applied to text-to-speech synthesis. The application of our research is the personalisation of speech-to-speech translation in which we employ a HMM statistical framework for ...

2013

Fast three-dimensional imaging of gold nanoparticles in living cells with photothermal optical lock-in Optical Coherence Microscopy

Theo Lasser, Christian Santschi, Christophe Pache, Martin Villiger, Arno Pino Bouwens, Noelia Laura Bocchio, Matthew Gibson, Corinne Berclaz, Joan Goulley

We introduce photothermal optical lock-in Optical Coherence Microscopy (poli-OCM), a volumetric imaging technique, which combines the depth sectioning of OCM with the high sensitivity of photothermal microscopy while maintaining the fast acquisition speed ...

Optical Society of America2012

Side-Chain Peptide-Synthetic Polymer Conjugates via Tandem "Ester-Amide/Thiol-Ene" Post-Polymerization Modification of Poly(pentafluorophenyl methacrylate) Obtained Using ATRP

Harm-Anton Klok, Matthew Gibson, Maarten Danial

Herein the concept of tandem postpolymerization modification as a versatile route to synthesize well-defined, highly functionalized polymers is introduced. Poly(pentafluorophenyl methacrylate) obtained by atom transfer radical polymerization was first modi ...

2011

Sequentially Modified, Polymer-Stabilized Gold Nanoparticle Libraries: Convergent Synthesis and Aggregation Behavior

Harm-Anton Klok, Matthew Gibson, Maarten Danial

This manuscript describes a versatile, yet experimentally facile, method for producing libraries of polymer coated (core-shell type) gold nanoparticles. The synthetic principle relies on two, sequential postmodification reactions, which ensures homogeneity ...

2011

Speaker adaptation and the evaluation of speaker similarity in the EMIME speech-to-speech translation project

Philip Neil Garner, John David Scott Dines, Hui Liang, Lakshmi Babu Saheer, Matthew Gibson, Simon King

This paper provides an overview of speaker adaptation research carried out in the EMIME speech-to-speech translation (S2ST) project. We focus on how speaker adaptation transforms can be learned from speech in one language and applied to the acous- tic mode ...

2010

Personalising speech-to-speech translation in the EMIME project

Philip Neil Garner, John David Scott Dines, Hui Liang, Lakshmi Babu Saheer, Matthew Gibson, Simon King

In the EMIME project we have studied unsupervised cross-lingual speaker adaptation. We have employed an HMM statistical framework for both speech recognition and synthesis which provides transformation mechanisms to adapt the synthesized voice in TTS (text ...

2010

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Matthew Gibson

A minimalistic cyclic ice-binding peptide from phage display

Impact of polymer-modified gold nanoparticles on brain endothelial cells: exclusion of endoplasmic reticulum stress as a potential risk factor

Selective detection of epimeric pentose saccharides at physiological pH using a fluorescent receptor

Personalising speech-to-speech translation: Unsupervised cross-lingual speaker adaptation for HMM-based speech synthesis

Size- and Coating-Dependent Uptake of Polymer-Coated Gold Nanoparticles in Primary Human Dermal Microvascular Endothelial Cells

Fast three-dimensional imaging of gold nanoparticles in living cells with photothermal optical lock-in Optical Coherence Microscopy

Side-Chain Peptide-Synthetic Polymer Conjugates via Tandem "Ester-Amide/Thiol-Ene" Post-Polymerization Modification of Poly(pentafluorophenyl methacrylate) Obtained Using ATRP

Sequentially Modified, Polymer-Stabilized Gold Nanoparticle Libraries: Convergent Synthesis and Aggregation Behavior

Speaker adaptation and the evaluation of speaker similarity in the EMIME speech-to-speech translation project

Personalising speech-to-speech translation in the EMIME project

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A minimalistic cyclic ice-binding peptide from phage display

Impact of polymer-modified gold nanoparticles on brain endothelial cells: exclusion of endoplasmic reticulum stress as a potential risk factor

Selective detection of epimeric pentose saccharides at physiological pH using a fluorescent receptor

Personalising speech-to-speech translation: Unsupervised cross-lingual speaker adaptation for HMM-based speech synthesis

Speaker adaptation and the evaluation of speaker similarity in the EMIME speech-to-speech translation project

Size- and Coating-Dependent Uptake of Polymer-Coated Gold Nanoparticles in Primary Human Dermal Microvascular Endothelial Cells

Fast three-dimensional imaging of gold nanoparticles in living cells with photothermal optical lock-in Optical Coherence Microscopy

Side-Chain Peptide-Synthetic Polymer Conjugates via Tandem "Ester-Amide/Thiol-Ene" Post-Polymerization Modification of Poly(pentafluorophenyl methacrylate) Obtained Using ATRP

Personalising speech-to-speech translation in the EMIME project

Sequentially Modified, Polymer-Stabilized Gold Nanoparticle Libraries: Convergent Synthesis and Aggregation Behavior