Publications by Yann Jérôme Michel Pascal Cotte

Marker-free phase nanoscopy

Pierre Magistretti, Christian Depeursinge, Nicolas Pavillon, Pierre Marquet, Pascal Jourdain, Daniel Boss, Muhammed Fatih Toy, Yann Jérôme Michel Pascal Cotte

We introduce a microscopic method that determines quantitative optical properties beyond the optical diffraction limit and allows direct imaging of unstained living biological specimens. In established holographic microscopy, complex fields are measured us ...

Nature Publishing Group2013

Resolution and Complex Deconvolution in Holographic Microscopy

Yann Jérôme Michel Pascal Cotte

Interest in high resolution imaging techniques has recently multiplied due to their importance in bio-medical research. Quantitative phase measurements by holographic microscopy is an extraordinary tool to gain new understanding of transparent biological s ...

EPFL2012

Complex index refraction tomography with sub ?/6-resolution

Christian Depeursinge, Nicolas Pavillon, Yann Jérôme Michel Pascal Cotte

The present invention discloses a method to improve the image resolution of a microscope. This improvement is based on the mathematical processing of the complex field computed from the measurements with a microscope of the wave emitted or scattered by the ...

2011

Realistic 3D coherent transfer function inverse filtering of complex fields

Christian Depeursinge, Daniel Boss, Muhammed Fatih Toy, Yann Jérôme Michel Pascal Cotte, Cristian Arfire, Shanshan Kou

We present a novel technique for three-dimensional (3D) image processing of complex fields. It consists in inverting the coherent image formation by filtering the complex spectrum with a realistic 3D coherent transfer function (CTF) of a high-NA digital ho ...

Optical Society of America2011

Beyond the lateral resolution limit by phase imaging

Christian Depeursinge, Muhammed Fatih Toy, Yann Jérôme Michel Pascal Cotte

We present a theory stating how to overcome the classical Rayleigh-resolution limit. It is based upon a new resolution criterion in phase of coherent imaging process and its spatial resolution is thought to be only SNR limited. Recently, the experimental o ...

SPIE2011

Beyond the lateral resolution limit by phase imaging

Christian Depeursinge, Muhammed Fatih Toy, Yann Jérôme Michel Pascal Cotte

We present a theory to extend the classical Abbe resolution limit by introducing a spatially varying phase into the illumination beam of a phase imaging system. It allows measuring lateral and axial distance differences between point sources to a higher ac ...

2011

Microscopy image resolution improvement by deconvolution of complex fields

Christian Depeursinge, Nicolas Pavillon, Muhammed Fatih Toy, Yann Jérôme Michel Pascal Cotte

Based on truncated inverse filtering, a theory for deconvolution of complex fields is studied. The validity of the theory is verified by comparing with experimental data from digital holographic microscopy (DHM) using a high-NA system (NA=0.95). Comparison ...

Optical Society of America2010

Sub-Rayleigh resolution by phase imaging

Christian Depeursinge, Nicolas Pavillon, Etienne Shaffer, Muhammed Fatih Toy, Yann Jérôme Michel Pascal Cotte

We report the experimental observation of systematically occurring phase singularities in coherent imaging of sub-Rayleigh distanced objects. A theory that relates the observation to the sub-Rayleigh distance is presented and compared with experimental mea ...

Optical Society of America2010

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