Person

Noelia Laura Bocchio

This person is no longer with EPFL

Related publications (19)

Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging

Theo Lasser, Marcel Leutenegger, Noelia Laura Bocchio, Aurélien Godinat, Patrick Alain Sandoz, Azat Sharipov, Stefan Geissbuehler

Super-resolution optical fluctuation imaging (SOFI) provides an elegant way of overcoming the diffraction limit in all three spatial dimensions by computing higher-order cumulants of image sequences of blinking fluorophores acquired with a classical widefi ...

2014

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By switching fluorophores on and off in either a deterministic or a stochastic manner, superresolution microscopy has enabled the imaging of biological structures at resolutions well beyond the diffraction limit. Superresolution optical fluctuation imaging ...

2013

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Super-resolution optical fluctuation imaging (SOFI) achieves three-dimensional super-resolution by computing higher-order spatio-temporal cross-cumulants of stochastically blink-ing fluorophores. In contrast to localization microscopy, SOFI is compatible w ...

2013

Balanced Super-resolution Optical Fluctuation Imaging (bSOFI)

Theo Lasser, Marcel Leutenegger, Stefan Geissbühler, Noelia Laura Bocchio, Corinne Berclaz, Claudio Dellagiacoma, Matthias Geissbühler

Super-resolution optical fluctuation imaging (SOFI) achieves 3D super-resolution by computing higher-order cumulants of stochastically blinking fluorophores. In contrast to localization microscopy, SOFI is compatible with weakly emitting fluorophores and a ...

2012

Mapping molecular statistics with balanced super-resolution optical fluctuation imaging (bSOFI)

Theo Lasser, Marcel Leutenegger, Noelia Laura Bocchio, Corinne Berclaz, Claudio Dellagiacoma, Stefan Geissbuehler

Super-resolution optical fluctuation imaging (SOFI) achieves 3D super-resolution by computing temporal cumulants or spatio-temporal cross-cumulants of stochastically blinking fluorophores. In contrast to localization microscopy, SOFI is compatible with wea ...

2012

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We introduce photothermal optical lock-in Optical Coherence Microscopy (poli-OCM), a volumetric imaging technique, which combines the depth sectioning of OCM with the high sensitivity of photothermal microscopy while maintaining the fast acquisition speed ...

Optical Society of America2012

Nonlinear Correlation Spectroscopy (NLCS)

Theo Lasser, Marcel Leutenegger, Iwan Märki, Jean-Pierre Wolf, Noelia Laura Bocchio, Luigi Bonacina, Stefan Geissbuehler

We present a novel concept for optical spectroscopy called nonlinear correlation spectroscopy (NLCS). NLCS analyses coherent field fluctuations of the second and third harmonic light generated by diffusing nanoparticles. Particles based on noncentrosymmetr ...

American Chemical Society2012

Characterization of Nanoparticles Using Non-linear Correlation Spectroscopy

Theo Lasser, Marcel Leutenegger, Iwan Märki, Jean-Pierre Wolf, Noelia Laura Bocchio, Luigi Bonacina

Nanoparticles are interesting for biomedical imaging as novel non- fluorescent non-bleaching labels. We present the characterization of freely diffusing nanoparticles using third harmonic generation correlation spectroscopy by illumination with a focussed ...

2011

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We present a combination of self-interference microscopy with lateral super-resolution microscopy and introduce a novel approach for localizing a single nano-emitter to within a few nanometers in all three dimensions over a large axial range. We demonstrat ...

Optical Society of America2010

Near-field mediated enhancement of two-photon induced fluorescence on plasmonic nanostructures

Noelia Laura Bocchio

We investigate two-photon-induced fluorescence for organic chromophores next to elongated gold disks which support plasmonic resonances. By polyelectrolyte coating, the dye is placed in a defined concentration at a defined distance from the surface. A fluo ...

American Chemical Society2010

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