Suliana Manley

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Related publications (87)

Multi-phosphorylation reaction and clustering tune Pom1 gradient mid-cell levels according to cell size

Suliana Manley, Anna Archetti, Lina Carlini, Charlotte Sophia Floderer, Thaïs Reichler

Protein concentration gradients pattern developing organisms and single cells. In Schizosaccharomyces pombe rod-shaped cells, Pom1 kinase forms gradients with maxima at cell poles. Pom1 controls the timing of mitotic entry by inhibiting Cdr2, which forms s ...

2019

Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging

Aleksandra Radenovic, Suliana Manley, Evgenii Glushkov, Anna Archetti, Anton Stroganov

Super-resolution microscopies based on the localization of single molecules have been widely adopted due to their demonstrated performance and their accessibility resulting from open software and simple hardware. The PAINT method for localization microscop ...

Nature Research2019

Strategies for increasing the throughput of super-resolution microscopies

Suliana Manley, Dora Mahecic, Juliette Griffie

Fluorescence microscopy methods have been developed to circumvent the diffraction limit by exploiting nonlinearities in the interactions between light and fluorophores. Initially, these methods were up to orders of magnitude slower than standard microscopi ...

ELSEVIER SCI LTD2019

Waveguide-Based Platform for Large-FOV Imaging of Optically Active Defects in 2D Materials

Aleksandra Radenovic, Suliana Manley, Martina Lihter, Evgenii Glushkov, Anton Stroganov, Mukeshchand Thakur, Vytautas Navikas, Anna Archetti, Juan Francisco Gonzalez Marin, Jean Camille Benjamin Comtet

Single-molecule localization microscopy (SMLM) is a powerful tool that is routinely used for nanoscale optical imaging of biological samples. Recently, this approach has been applied to study optically active defects in two-dimensional (2D) materials. Such ...

AMER CHEMICAL SOC2019

Single-molecule dynamics and genome-wide transcriptomics reveal that NF-kB (p65)-DNA binding times can be decoupled from transcriptional activation

Suliana Manley, Beat Fierz, David Michael Suter, Christian Sieben, Aleksandr Benke, Andrea Callegari

Transcription factors (TFs) regulate gene expression in both prokaryotes and eukaryotes by recognizing and binding to specific DNA promoter sequences. In higher eukaryotes, it remains unclear how the duration of TF binding to DNA relates to downstream tran ...

2019

EZH2 oncogenic mutations drive epigenetic, transcriptional, and structural changes within chromatin domains

Suliana Manley, Elisa Oricchio, Kyle Michael Douglass, Natalya Katanayeva, Daniele Tavernari, Elena Battistello, Stephanie Jocelyne Sungalee, Maria Christine Donaldson, Timo Henry René Rey, Giovanni Ciriello

Chromatin is organized into topologically associating domains (TADs) enriched in distinct histone marks. In cancer, gain-of-function mutations in the gene encoding the enhancer of zeste homolog 2 protein (EZH2) lead to a genome-wide increase in histone-3 L ...

2019

Autonomous illumination control for localization microscopy

Suliana Manley, Kyle Michael Douglass, Baptiste Romain Samuel Ottino, Marcel Stefko

Super-resolution fluorescence microscopy improves spatial resolution, but this comes at a loss of image throughput and presents unique challenges in identifying optimal acquisition parameters. Microscope automation routines can offset these drawbacks, but ...

OPTICAL SOC AMER2018

Super-resolution microscopy to decipher multi-molecular assemblies

Suliana Manley, Kyle Michael Douglass, Paul Guichard, Christian Sieben

2018

Constriction Rate Modulation Can Drive Cell Size Control and Homeostasis in C. crescentus

Suliana Manley, Seamus John Holden, Anna Archetti, Aster Louis K Vanhecke, Ambroise Justin Lambert, Felix Max Schaber

Rod-shaped bacteria typically grow first via sporadic and dispersed elongation along their lateral walls and then via a combination of zonal elongation and constriction at the division site to form the poles of daughter cells. Although constriction compris ...

2018

Polyphosphate granule formation affects chromosome dynamics during starvation in the opportunistic human pathogen Pseudomonas aeruginosa

Suliana Manley, Aster Louis K Vanhecke

AMER SOC CELL BIOLOGY2018

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Single-molecule dynamics and genome-wide transcriptomics reveal that NF-kB (p65)-DNA binding times can be decoupled from transcriptional activation

Suliana Manley, Beat Fierz, David Michael Suter, Christian Sieben, Aleksandr Benke, Andrea Callegari

2019

Polyphosphate granule formation affects chromosome dynamics during starvation in the opportunistic human pathogen Pseudomonas aeruginosa

Suliana Manley, Aster Louis K Vanhecke

AMER SOC CELL BIOLOGY2018

Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging

Aleksandra Radenovic, Suliana Manley, Evgenii Glushkov, Anna Archetti, Anton Stroganov

Nature Research2019