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Daniël Noordermeer

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Related publications (4)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Large scale genomic reorganization of topological domains at the HoxD locus

Denis Duboule, Marion Leleu, Daniël Noordermeer, Lucille Delisle, Pierre Raymond Fabre, Leonardo Beccari, Benjamin Howard Mormann

BACKGROUND: The transcriptional activation of HoxD genes during mammalian limb development involves dynamic interactions with two topologically associating domains (TADs) flanking the HoxD cluster. In particular, the activation of the most posterior HoxD g ...

2017

Enhancer loops appear stable during development and are associated with paused polymerase

Daniël Noordermeer

Developmental enhancers initiate transcription and are fundamental to our understanding of developmental networks, evolution and disease. Despite their importance, the properties governing enhancer-promoter interactions and their dynamics during embryogene ...

Nature Publishing Group2014

Chromatin looping and organization at developmentally regulated gene loci

Denis Duboule, Daniël Noordermeer

Developmentally regulated genes are often controlled by distant enhancers, silencers and insulators, to implement their correct transcriptional programs. In recent years, the development of 3C and derived techniques (4C, 5C, HiC, ChIA- PET, etc.) has confi ...

2013