Rational metabolic engineering methods are increasingly employed in designing the commercially viable processes for the production of chemicals relevant to pharmaceutical, biotechnology, and food and beverage industries. With the growing availability of om ...
Accurate determination of physiological states of cellular metabolism requires detailed information about metabolic fluxes, metabolite concentrations and distribution of enzyme states. Integration of fluxomics and metabolomics data, and thermodynamics-base ...
Metabolic Engineering is fostered by an increasing effort and progress in the collection of large and accurate 'omics' datasets. The abundance of available measurements and advances in measurement techniques only alleviate to a certain extent the uncertai ...