Publications de Stefano Andreozzi

iSCHRUNK – In Silico Approach to Characterization and Reduction of Uncertainty in the Kinetic Models of Genome-scale Metabolic Networks

Vassily Hatzimanikatis, Ljubisa Miskovic, Stefano Andreozzi

Accurate determination of physiological states of cellular metabolism requires detailed information about metabolic fluxes, metabolite concentrations and distribution of enzyme states. Integration of fluxomics and metabolomics data, and thermodynamics-base ...

Academic Press Inc Elsevier Science2016

Identification of metabolic engineering targets for the enhancement of 1,4-butanediol production in recombinant E. coli using large-scale kinetic models

Vassily Hatzimanikatis, Ljubisa Miskovic, Keng Cher Soh, Stefano Andreozzi

Rational metabolic engineering methods are increasingly employed in designing the commercially viable processes for the production of chemicals relevant to pharmaceutical, biotechnology, and food and beverage industries. With the growing availability of om ...

Elsevier2016

Computational studies on Escherichia coli metabolism : from constitutive bricks to large-scale behaviour

Stefano Andreozzi

Metabolic Engineering is fostered by an increasing effort and progress in the collection of large and accurate 'omics' datasets. The abundance of available measurements and advances in measurement techniques only alleviate to a certain extent the uncertai ...

EPFL2015

Guaranteed and randomized methods for stability analysis of uncertain metabolic networks

Stefano Andreozzi

2011