Person
Tom Hilbert
Related publications (41)
Compressed sensing (CS) MP2RAGE versus standard MPRAGE: A of derived brain volume measurements
Tobias Kober, Tom Hilbert, Gian Franco Piredda
Purpose: T1 Magnetization Prepared Two Rapid Acquisition Gradient Echo (MP2RAGE) with compress sensing (CS) has been proposed as an improvement of the standard MPRAGE sequence with multiple advantages including reduced acquisition time needed to provide a ...
ELSEVIER SCI LTD2022Differentiation between benign and malignant vertebral compression fractures using qualitative and quantitative analysis of a single fast spin echo T2-weighted Dixon sequence
Objectives To determine and compare the qualitative and quantitative diagnostic performance of a single sagittal fast spin echo (FSE) T2-weighted Dixon sequence in differentiating benign and malignant vertebral compression fractures (VCF), using multiple r ...
SPRINGER2021Simulated Half-Fourier Acquisitions Single-shot Turbo Spin Echo (HASTE) of the Fetal Brain: Application to Super-Resolution Reconstruction
Meritxell Bach Cuadra, Tobias Kober, Tom Hilbert, Thomas Yu, Sébastien Tourbier, Reto Meuli, Patric Hagmann, Hamza Kebiri
Accurate characterization of in utero human brain maturation is critical as it involves complex interconnected structural and functional processes that may influence health later in life. Magnetic resonance imaging is a powerful tool complementary to the u ...
SPRINGER INTERNATIONAL PUBLISHING AG2021Simultaneous 3D acquisition of H-1 MRF and Na-23 MRI
Purpose To develop a 3D MR technique to simultaneously acquire proton multiparametric maps (T-1, T-2, and proton density) and sodium density weighted images over the whole brain. Methods We implemented a 3D stack-of-stars MR pulse sequence which consists o ...
WILEY2021Comparison of non-parametric T2 relaxometry methods for myelin water quantification
Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Marco Pizzolato, Gian Franco Piredda, Thomas Yu, Alessandro Daducci, Nicolas Kunz
Multi-component T2 relaxometry allows probing tissue microstructure by assessing compartment-specific T2 relaxation times and water fractions, including the myelin water fraction. Non-negative least squares (NNLS) with zero-order Tikhonov regularization is ...
2021Accelerated T(2)Mapping of the Lumbar Intervertebral Disc Highly Undersampled K-Space Data for Robust T(2)Relaxation Time Measurement in Clinically Feasible Acquisition Times
Tobias Kober, Tom Hilbert, Michael Weber
Objectives T(2)mapping of the intervertebral disc (IVD) can depict quantitative changes reflecting biochemical change due to loss of glycosaminoglycan content. Conventional T(2)mapping is usually performed using a 2-dimensional multi-echo-spin echo sequenc ...
2020Clinical implementation of accelerated T-2 mapping: Quantitative magnetic resonance imaging as a biomarker for annular tear and lumbar disc herniation
Tobias Kober, Tom Hilbert, Michael Weber
Objectives This study evaluates GRAPPATINI, an accelerated T-2 mapping sequence combining undersampling and model-based reconstruction to facilitate the clinical implementation of T-2 mapping of the lumbar intervertebral disc. Methods Fifty-eight individua ...
SPRINGER2020Fast and high-resolution myelin water imaging: Accelerating multi-echo GRASE with CAIPIRINHA
Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Marco Pizzolato, Gian Franco Piredda, Reto Meuli, Alessandro Daducci
Purpose Although several MRI methods have been explored to achievein vivomyelin quantification, imaging the whole brain in clinically acceptable times and sufficiently high resolution remains challenging. To address this problem, this work investigates the ...
2020NovelT2Mapping for Evaluating Cervical Cancer Features by Providing QuantitativeT2Maps and Synthetic Morphologic Images: A Preliminary Study
Tobias Kober, Tom Hilbert, Yong Zhang, Meng Yang, Jie Liu
Background The application value of T(2)mapping in evaluating cervical cancer (CC) features remains unclear. Purpose To investigate the role of T(2)values in evaluating CC classification, grade, and lymphovascular space invasion (LVSI) in comparison to app ...
WILEY2020Accelerated MP2RAGE imaging using Cartesian phyllotaxis readout and compressed sensing reconstruction
Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, Reto Meuli
Purpose MP2RAGE T-1-weighted imaging has been shown to be beneficial for various applications, mainly because of its good grey-white matter contrast, its B-1-robustness and ability to derive T(1)maps. Even using parallel imaging, the method requires long a ...
WILEY2020