Publications by Zhi Luo | EPFL Graph Search

Quantifying the Solution Structure of Metal Nanoclusters Using Small-Angle Neutron Scattering

Francesco Stellacci, Stefan Guldin, Zhi Luo, Ye Yang, Huayan Yang

Metal nanoclusters are a unique class of synthetic material, as their crystal structures can be resolved using X-ray diffraction, and their chemical formula can be precisely determinated from mass spectroscopy. However, a complete structure characterizatio ...

Wiley-VCH Verlag GmbH2022

Comparative characterisation of non-monodisperse gold nanoparticle populations by X-ray scattering and electron microscopy

Francesco Stellacci, Stefan Guldin, Zhi Luo, Ye Yang, Suiyang Liao, Runzhang Qi

Accurate nanoparticle size determination is essential across various research domains, with many functionalities in nanoscience and biomedical research being size-dependent. Although electron microscopy is capable of resolving a single particle down to the ...

2020

Reproducibility warning: The curious case of polyethylene glycol 6000 and spheroid cell culture

Francesco Stellacci, Quy Ong Khac, Ahmet Bekdemir, Zhi Luo

Reproducibility of results is essential for a well-designed and conducted experiment. Several reasons may originate failure in reproducing data, such as selective reporting, low statistical power, or poor analysis. In this study, we used PEG6000 samples fr ...

2020

Quantification of surface composition and segregation on AuAg bimetallic nanoparticles by MALDI MS

Francesco Stellacci, Zhi Luo, Suiyang Liao

In this work we show that it is possible to use MALDI-TOF as a tool to quantify the atomic composition and to describe the phase segragation of the surface of ligand-coated, bimetallic AuAg nanoparticles. Our investigation shows that AuAg nanoparticles of ...

ROYAL SOC CHEMISTRY2020

Synthesis and Characterization of Amphiphilic Gold Nanoparticles

Francesco Stellacci, Paulo Henrique Jacob Silva, Zhi Luo, Matteo Gasbarri, Zekiye Pelin Güven, Urszula Beata Cendrowska, Samuel Thomas Jones

Gold nanoparticles covered with a mixture of 1-octanethiol (OT) and 11-mercapto-1-undecane sulfonic acid (MUS) have been extensively studied because of their interactions with cell membranes, lipid bilayers, and viruses. The hydrophilic ligands make these ...

JOURNAL OF VISUALIZED EXPERIMENTS2019

Determination and evaluation of the nonadditivity in wetting of molecularly heterogeneous surfaces

Francesco Stellacci, Michele Ceriotti, Sylvie Roke, Quy Ong Khac, Halil Ibrahim Okur, David Mark Wilkins, Zhi Luo, Anna Murello, Filip Kovacik

The interface between water and folded proteins is very complex. Proteins have "patchy" solvent-accessible areas composed of domains of varying hydrophobicity. The textbook understanding is that these domains contribute additively to interfacial properties ...

National Academy of Sciences2019

Multidimensional Characterization of Mixed Ligand Nanoparticles Using Small Angle Neutron Scattering

Francesco Stellacci, Quy Ong Khac, Stefan Guldin, Zhi Luo, Ye Yang

The properties of ligand protected gold nanoparticles are determined by the synergistic interplay of their structural components, including the metal core, the ligand shell, and the solvation layer. However, the simultaneous characterization of all these c ...

AMER CHEMICAL SOC2019

Mass spectrometry and Monte Carlo method mapping of nanoparticle ligand shell morphology

Francesco Stellacci, Zhi Luo, Yanfei Zhao, Jing Hou, Yue Wang

Janus, patchy, stripe-like, or random arrangements of molecules within the ligand shell of nanoparticles affect many properties. Among all existing ligand shell morphology characterization methods, the one based on mass spectroscopy is arguably the simples ...

Nature Publishing Group2018

Advanced characterization methods for self-assembled organization on nanoparticles

Zhi Luo

The complex organizations of amino acid residues on protein surfaces give rise to a wide space of functions for proteins. Great efforts are devoted in biology to understand such structure-property relationships. Many advanced characterization techniques ha ...

EPFL2018

Quantitative 3D determination of self-assembled structures on nanoparticles using small angle neutron scattering

Francesco Stellacci, Zhi Luo, Raffaella Buonsanti, Anna Loiudice, Quy Ong Khac

2018