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Cells in the body collectively sustain mechanical deformations in almost all physiological functions. From the morphogenesis stage, cells' ability to sustain stress is essential for the body's well-being. Several pathologies have been associated with abnor ...
ROYAL SOC CHEMISTRY2019
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Test assays capable of providing quantitative characterization of the contraction of cardiac and smooth muscle cells are of great need for drug development and screening. Several methodologies have been proposed for achieving measurement of cell contractil ...
We present a mechanically active cell culture substrate that produces complex strain patterns and generates extremely high strain rates. The transparent miniaturized cell stretcher is compatible with live cell microscopy and provides a very compact and por ...
Everyday life physiological functions such as breathing, muscle contraction, and blood circulation rely on the ability of single cells to organize into higher complexity structures and sustain mechanical deformations. Cell monolayers are the simplest tissu ...