Publications by Timothé Laforest

Lock-in amplified differential phase contrast

Christophe Moser, Timothé Laforest, Damien Claude-Marie Loterie, Chiara Bonati

We introduce a lock-in method to increase the phase contrast in incoherent Differential Phase Contrast (DPC) imaging. The use of a smart pixel detector with in-pixel signal demodulation, paired with synchronized illumination, provides the basis of a bit-ef ...

SPIE-INT SOC OPTICAL ENGINEERING2022

In Vivo Retinal Pigment Epithelium Imaging using Transscleral Optical Imaging in Healthy Eyes

Christophe Moser, Timothé Laforest, Laura Emmanuelle Kowalczuk, Mathieu Künzi

Objective: To image healthy retinal pigment epithelial (RPE) cells in vivo using Transscleral OPtical Imaging (TOPI) and to analyze statistics of RPE cell features as a function of age, axial length (AL), and eccentricity. Design: Single-center, explorator ...

ELSEVIER2022

Human retinal pigment epithelium cells can be imaged in vivo with a novel adaptive optics camera using transscleral illumination

Christophe Moser, Timothé Laforest, Laura Emmanuelle Kowalczuk, Mathieu Künzi

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2022

Lock-in incoherent differential phase contrast imaging

Christophe Moser, Timothé Laforest, Damien Claude-Marie Loterie, Chiara Bonati

We introduce a lock-in method to increase the phase contrast in incoherent differential phase contrast (DPC) imaging. This method improves the phase sensitivity by the analog removal of the background. The use of a smart pixel detector with in-pixel signal ...

CHINESE LASER PRESS2022

Multi-modal retinal imaging platform

Christophe Moser, Timothé Laforest, Mathieu Künzi

The invention relates to oblique transscleral illumination of an eye fundus with at least one physical point light source around the eye allowing for dark field imaging combined with optical coherence tomography imaging. ...

2021

Transscleral optical phase imaging in non-neovascular age-related macular degeneration

Christophe Moser, Timothé Laforest, Laura Emmanuelle Kowalczuk, Mathieu Künzi

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2021

Fully automated detection, segmentation, and analysis of in vivo RPE single cells

Christophe Moser, Timothé Laforest, Laura Emmanuelle Kowalczuk, Florentino Luciano Caetano Dos Santos

Objective To develop a fully automated method of retinal pigmented epithelium (RPE) cells detection, segmentation and analysis based on in vivo cellular resolution images obtained with the transscleral optical phase imaging method (TOPI). Methods Fourteen ...

NATURE PUBLISHING GROUP2021

System and methods for differential imaging using a lock-in camera

Christophe Moser, Timothé Laforest, Damien Claude-Marie Loterie, Chiara Bonati

The present invention describes an imaging system that allows visualization of a wide range of samples both in terms of morphology and in terms of material (e.g. density distribution, varying chemical composition, or anything that induces a change of optic ...

2021

Transscleral optical phase imaging revealing the choriocapillaris structure

Christophe Moser, Timothé Laforest, Mathieu Künzi

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2021

Transscleral Optical Phase Imaging of healthy human Retinal Pigment Epithelium

Christophe Moser, Timothé Laforest, Laura Emmanuelle Kowalczuk, Mathieu Künzi

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2021