Publications by Vivek Vijay Thacker

Human alveolar lining fl uid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells

Vivek Vijay Thacker, Richa Mishra

The elderly population is highly susceptible to developing respiratory diseases, including tuberculosis, a devastating disease caused by the airborne pathogen Mycobacterium tuberculosis ( M.tb ) that kills one person every 18 seconds. Once M.tb reaches the ...

Elsevier Science Inc2024

The cGAS–STING pathway drives type I IFN immunopathology in COVID-19

Andrea Ablasser, Muhammet Fatih Gülen, Vivek Vijay Thacker, Théo Nass, Martin Schaller, Kunal Sharma

COVID-19, which is caused by infection with SARS-CoV-2, is characterized by lung pathology and extrapulmonary complications1,2. Type I interferons (IFNs) have an essential role in the pathogenesis of COVID-19 (refs 3–5). Although rapid induction of type I ...

2022

Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

John McKinney, Neeraj Dhar, Vivek Vijay Thacker, François Signorino-Gelo, Kunal Sharma, Thomas Marie Simonet

Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells to form intracellular bacterial communities (IBCs) during early stages of urinary tract infections. However, the dynamic responses of IBCs to host stresses and anti ...

2021

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Vivek Vijay Thacker

Human alveolar lining fl uid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells

The cGAS–STING pathway drives type I IFN immunopathology in COVID-19

Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

Lipid-coated nanocapillaries for DNA sensing

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Chat with Graph Search

Lipid-coated nanocapillaries for DNA sensing

Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

The cGAS–STING pathway drives type I IFN immunopathology in COVID-19

Human alveolar lining fl uid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells