Publications by Danilo Demarchi

Smart Portable Pen for Continuous Monitoring of Anaesthetics in Human Serum With Machine Learning

Sandro Carrara, Mandresy Ivan Ny Hanitra, Danilo Demarchi, Simone Aiassa

Continuous monitoring of anaesthetics infusion is demanded by anaesthesiologists to help in defining personalized dose, hence reducing risks and side effects. We propose the first piece of technology tailored explicitly to close the loop between anaesthesi ...

2021

Biosensors for Bimolecular Computing: a Review and Future Perspectives

Sandro Carrara, Danilo Demarchi, Simone Aiassa

Biomolecular computing is the field of engineering where computation, storage, communication, and coding are obtained by exploiting interactions between biomolecules, especially DNA, RNA, and enzymes. They are a promising solution in a long-term vision, br ...

SPRINGER2020

New Approach for Making Standard the Development of Biosensing Devices by a Modular Multi-Purpose Design

Sandro Carrara, Francesca Stradolini, Ioulia Tzouvadaki, Danilo Demarchi, Francesca Criscuolo, Abuduwaili Tuoheti, Simone Aiassa

The fast widening of biosensing applications, such as healthcare, drug delivery, food, and military industries, is increasing the need for generality and compatibility among different sensors. To address this challenge, we present here an innovative approa ...

2020

Miniaturised Wireless Power Transfer Systems for Neurostimulation: A Review

Sandro Carrara, Diego Ghezzi, Gian Luca Barbruni, Danilo Demarchi

In neurostimulation, wireless power transfer is an efficient technology to overcome several limitations affecting medical devices currently used in clinical practice. Several methods were developed over the years for wireless power transfer. In this review ...

2020

Pencil Graphite Needle-Shaped Biosensor for Anaesthetic Monitoring in Human Serum

Sandro Carrara, Danilo Demarchi, Simone Aiassa

Direct and online continuous monitoring of anaesthetic intake by the patient's blood stream improves practices in the critical procedure of anaesthesia. Several systems have been proposed to address this challenge. Electrochemical techniques are highly app ...

IEEE2020

New Measurement Method in Drug Sensing by Direct Total-Charge Detection in Voltammetry

Sandro Carrara, Danilo Demarchi, Simone Aiassa, José David González Martínez

Electrochemical biosensors are promoting point-of-care and wearable instrumentation due to their high versatility in measuring human metabolites. There is a considerable number of biological compounds that can be detected and measured through voltammetry b ...

IEEE2020

Continuous monitoring of propofol in human serum with fouling compensation by support vector classifier

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Danilo Demarchi, Francesca Criscuolo, Simone Aiassa, Francesco Grassi, Tiberiu Totu, Gabriele Sandri

We present a new method for electrochemical sensing, which compensates the fouling effect of propofol through machine learning (ML) model. Direct and continuous monitoring of propofol is crucial in the development of automatic systems for control of drug i ...

Elsevier2020

Emulator Design and Generation of Synthetic Dataset in Multi-Ion Sensing

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Danilo Demarchi

Multi-ion potentiometric sensing becomes challenging for mixed-ion samples in which interfering electrolytes significantly alter the response of each single sensor. Therefore, an emulator based on the phase-boundary potential model is proposed to simulate ...

IEEE2020

An Event-Driven Closed-Loop System for Real-Time FES Control

Silvestro Micera, Andrea Crema, Danilo Demarchi

Active functional rehabilitation procedures, exoskeleton application and prosthesis employment are essential tools for the society life reinstatement of subjects affected by neuromuscular disorders or victims of serious physical accident. In this paper we ...

IEEE2019

Live Demonstration: Quasi-Digital Portable Pen to Monitor Anaesthetics Delivery

Sandro Carrara, Danilo Demarchi, Simone Aiassa, Francesco Grassi

The live demonstration presents the innovative concept of a portable pen-device able to sense anaesthetic compounds over time for improved anaesthesiology practice. A custom Printed Circuit Board (PCB) manage in the event-based quasi-digital domain the sam ...

IEEE2019