Publications by Jun Yong Kim | EPFL Graph Search

Hippo-YAP/TAZ signalling coordinates adipose plasticity and energy balance by uncoupling leptin expression from fat mass

Johan Auwerx, Xiaoxu Li, Maroun Bou Sleiman, Jun Yong Kim, Yoo Hoon Kim

Adipose tissues serve as an energy reservoir and endocrine organ, yet the mechanisms that coordinate these functions remain elusive. Here, we show that the transcriptional coregulators, YAP and TAZ, uncouple fat mass from leptin levels and regulate adipocy ...

Nature Portfolio2024

Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice

Johan Auwerx, Xiaoxu Li, Maroun Bou Sleiman, Jun Yong Kim

Brown adipose tissue (BAT) has abundant mitochondria with the unique capability of generating heat via uncoupled respiration. Here, Park et al. identify LETMD1 as a mitochondrial matrix protein enriched in brown adipose tissue (BAT) and reveal a crucial ro ...

Nature Portfolio2023

Differential roles of GDF15 and FGF21 in systemic metabolic adaptation to the mitochondrial integrated stress response

Johan Auwerx, Jun Yong Kim

Perturbation of mitochondrial proteostasis provokes cell autonomous and cell non-autonomous responses that contribute to homeostatic adaptation. Here, we demonstrate distinct metabolic effects of hepatic metabokines as cell non-autonomous factors in mice w ...

CELL PRESS2021

Growth differentiation factor 15 protects against the aging-mediated systemic inflammatory response in humans and mice

Johan Auwerx, Jun Yong Kim, Ludger Jan Elzuë Goeminne, Dongryeol Ryu

Mitochondrial dysfunction is associated with aging-mediated inflammatory responses, leading to metabolic deterioration, development of insulin resistance, and type 2 diabetes. Growth differentiation factor 15 (GDF15) is an important mitokine generated in r ...

2020

Transverse momentum dependent production cross sections of charged pions, kaons and protons produced in inclusive e(+)e(-) annihilation at root s=10.58 GeV

Olivier Schneider, Mithilesh Nayak, Yiming Li, Mingkui Wang, Chao Wang, Tagir Aushev, Sun Hee Kim, Jun Yong Kim, Ji Hyun Kim, Donghyun Kim

We report measurements of the production cross sections of charged pions, kaons, and protons as a function of fractional energy, the event-shape variable called thrust, and the transverse momentum with respect to the thrust axis. These measurements access ...

American Physical Society2019

Measurements of isospin asymmetry and difference of direct CP asymmetries in inclusive B -> X-s gamma decays

Olivier Schneider, Sun Hee Kim, Yiming Li, Mingkui Wang, Tara Nanut, Chao Wang, Kyung Taek Cho, Tagir Aushev, Chang-Hyun Park, Arnaud Michel Gelb

We report measurements of isospin asymmetry Delta(0-) and difference of direct CP asymmetries Delta A(CP) between charged and neutral B -> X-s gamma decays. This analysis is based on the data sample containing 772 x 10(6)B (B) over bar pairs that was colle ...

American Physical Society2019

Observation of Xi(1620)(0) and Evidence for Xi(1690)(0) in Xi(+)(c) -> Xi(-) pi(+) pi(+) Decays

Olivier Schneider, Yiming Li, Mingkui Wang, Chao Wang, Tagir Aushev, Sun Hee Kim, Tara Nanut, Jun Yong Kim, Ji Hyun Kim, Donghyun Kim

We report the first observation of the double strange baryon Xi(1620)(0) in its decay to Xi(-) pi(+) via Xi(+)(c) -> Xi(-)pi(+)pi(+) decays based on a 980 fb(-1) data sample collected with the Belle detector at the KEKB asymmetricenergy e(+)e(-) collider. ...

2019

Search for a Light CP-odd Higgs Boson and Low-Mass Dark Matter at the Belle Experiment

Olivier Schneider, Yiming Li, Roberto Gargiani, Chao Wang, Mithilesh Nayak, Gaétan Charles Antoine Giriat, Tagir Aushev, Sun Hee Kim, Tara Nanut, Ke Huang

We report on the first Belle search for a light CP-odd Higgs boson, A(0), that decays into low mass dark matter, chi, in final states with a single photon and missing energy. We search for events produced via the dipion transition (sic)(2S) -> (sic)(1S)pi( ...

2019

Measurement of time-dependent CP violation in B-0 -> K-S(0)pi(0)pi(0) decays

Olivier Schneider, Yiming Li, Mingkui Wang, Chao Wang, Tagir Aushev, Sun Hee Kim, Tara Nanut, Jun Yong Kim, Ji Hyun Kim, Donghyun Kim

We report a measurement of time-dependent CP violation in B-0 -> K-S(0)pi(0)pi(0) decays using a data sample of 772 x 10(6) B (B) over bar pairs collected by the Belle experiment running at the (sic)(4S) resonance at the KEKB e(+)e(-) collider. This decay ...

American Physical Society2019

Observation of B+ -> p(Lambda)over-barK(+) K- and B+ -> (p)over-bar Lambda K+ K+

Olivier Schneider, Yiming Li, Mingkui Wang, Chao Wang, Tagir Aushev, Sun Hee Kim, Tara Nanut, Jun Yong Kim, Ji Hyun Kim, Donghyun Kim

We report the study of B+ -> p (Lambda) over barK(+)K(-) and B+ -> (p) over barK(+)K(+) decays using a 772 x 10(6) B (B) over bar pair data sample recorded on the gamma(4S) resonance with the Belle detector at KEKB. The following branching fractions are me ...

American Physical Society2019