Alexandre Louis André Persat

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Related publications (27)

Mechanomicrobiology: how bacteria sense and respond to forces

Microbiology and biophysics are converging to advance our understanding of the mechanobiology of microorganisms. In this Review, Dufrene and Persat discuss the physical forces that bacteria experience in their natural environments and the structures that t ...

NATURE PUBLISHING GROUP2020

Cellular advective-diffusion drives the emergence of bacterial surface colonization patterns and heterogeneity

Alexandre Louis André Persat, Tamara Rossy

Microorganisms navigate and divide on surfaces to form multicellular structures called biofilms, the most widespread survival strategy found in the bacterial world. One common assumption is that cellular components guide the spatial architecture and arrang ...

Nature Research2019

Vibrio cholerae filamentation promotes chitin surface attachment at the expense of competition in biofilms

Alexandre Louis André Persat

Collective behavior in spatially structured groups, or biofilms, is the norm among microbes in their natural environments. Though biofilm formation has been studied for decades, tracing the mechanistic and ecological links between individual cell morpholog ...

National Academy of Sciences2019

Pseudomonas aeruginosa orchestrates twitching motility by sequential control of type IV pili movements

Alexandre Louis André Persat, Lorenzo Anton-Louis Talà

Prokaryotes have the ability to walk on surfaces using type IV pili (TFP), a motility mechanism known as twitching(1,2). Molecular motors drive TFP extension and retraction, but whether and how these movements are coordinated is unknown(3). Here, we reveal ...

NATURE PUBLISHING GROUP2019

Bacterial Mechanosensing with Type IV Pili

Alexandre Louis André Persat, Lorenzo Anton-Louis Talà, Xavier Jean-Yves Pierrat

CELL PRESS2018

A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling in Pseudomonas aeruginosa

Alexandre Louis André Persat, Joanne Netter Engel

Type IV pili (TFP) function as mechanosensors to trigger acute virulence programs in Pseudomonas aeruginosa. On surface contact, TFP retraction activates the Chp chemosensory system phosphorelay to upregulate 3', 5'-cyclic monophosphate (cAMP) production a ...

Wiley-Blackwell2016

An Ohmic model for electrokinetic flows of binary asymmetric electrolytes

Alexandre Louis André Persat

The transport of electrolytes in electric fields is a ubiquitous phenomenon commonly harnessed in microfluidics. A classic leaky dielectric model for flow generated by electric fields accurately predicts electrohydrodynamic transport phenomenon but is vali ...

Elsevier Science London2016

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A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling in Pseudomonas aeruginosa

Alexandre Louis André Persat, Joanne Netter Engel

Wiley-Blackwell2016

An Ohmic model for electrokinetic flows of binary asymmetric electrolytes

Alexandre Louis André Persat

Elsevier Science London2016