Person
Giuliana Rossi
Related publications (4)
Capturing Cardiogenesis in Gastruloids
Matthias Lütolf, Romain Guiet, Giuliana Rossi, Andrea Boni, Nicolas Antoine Vincent Broguiere, Mehmet Ugur Girgin
Organoids are powerful models for studying tissue development, physiology, and disease. However, current culture systems disrupt the inductive tissue-tissue interactions needed for the complex morphogenetic processes of native organogenesis. Here, we show ...
CELL PRESS2021The Transcription Factor Nfix Requires RhoA-ROCK1 Dependent Phagocytosis to Mediate Macrophage Skewing during Skeletal Muscle Regeneration
Macrophages (MPs) are immune cells which are crucial for tissue repair. In skeletal muscle regeneration, pro-inflammatory cells first infiltrate to promote myogenic cell proliferation, then they switch into an anti-inflammatory phenotype to sustain myogeni ...
2020Polarised three-dimensional cellular aggregates
Matthias Lütolf, Giuliana Rossi
Polarised three-dimensional cellular aggregates (or gastruloids) generated in vitro from one or more pluripotent stem cells are provided. Methods for obtaining polarised three-dimensional cellular aggregates and cells (e.g. progenitor cells and derivatives ...
2020Progress and potential in organoid research
Matthias Lütolf, Giuliana Rossi, Andrea Manfrin
Tissue and organ biology are very challenging to study in mammals, and progress can be hindered, particularly in humans, by sample accessibility and ethical concerns. However, advances in stem cell culture have made it possible to derive in vitro 3D tissue ...
2018