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Alexander Mathis

Related publications (40)

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Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer

Hatice Altug, Alexander Mathis, George Coukos, Xiaokang Li, Yen-Cheng Liu, David Gfeller, Pedro Romero, Alexandre Harari, Amélie Cachot, Margaux Saillard, Georg Alexander Rockinger

CD4 T cells have been implicated in cancer immunity for their helper functions. Moreover, their direct cytotoxic potential has been shown in some patients with cancer. Here, by mining single-cell RNA-seq datasets, we identified CD4 T cell clusters displayi ...

2021

Measuring and modeling the motor system with machine learning

Alexander Mathis, Alessandro Marin Vargas

The utility of machine learning in understanding the motor system is promising a revolution in how to collect, measure, and analyze data. The field of movement science already elegantly incorporates theory and engineering principles to guide experimental w ...

2021

Pretraining boosts out-of-domain robustness for pose estimation

Alexander Mathis, Mackenzie Mathis, Steffen Schneider, Matthias Bethge, Thomas Ray Biasi, Mert Yüksekgönül

Neural networks are highly effective tools for pose estimation. However, as in other computer vision tasks, robustness to out-of-domain data remains a challenge, especially for small training sets that are common for real-world applications. Here, we probe ...

IEEE COMPUTER SOC2021

Perspectives on Individual Animal Identification from Biology and Computer Vision

Alexander Mathis, Maxime Michel André Vidal

Identifying individual animals is crucial for many biological investigations. In response to some of the limitations of current identification methods, new automated computer vision approaches have emerged with strong performance. Here, we review current a ...

OXFORD UNIV PRESS INC2021

AcinoSet: A 3D Pose Estimation Dataset and Baseline Models for Cheetahs in the Wild

Alexander Mathis, Mackenzie Mathis

Animals are capable of extreme agility, yet understanding their complex dynamics, which have ecological, biomechanical and evolutionary implications, remains challenging. Being able to study this incredible agility will be critical for the development of n ...

IEEE2021

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Biological motor control is versatile and efficient. Muscles are flexible and undergo continuous changes requiring distributed adaptive control mechanisms. How proprioception solves this problem in the brain is unknown. Here we pursue a task-driven modelin ...

Neuroscience2020

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Extracting behavioral measurements non-invasively from video is stymied by the fact that it is a hard computational problem. Recent advances in deep learning have tremendously advanced our ability to predict posture directly from videos, which has quickly ...

2020

The ability to control a behavioral task or stimulate neural activity based on animal behavior in real-time is an important tool for experimental neuroscientists. Ideally, such tools are (1) noninvasive, (2) low-latency, and (3) provide interfaces to trigg ...

Neuroscience2020

Recent advances in computer vision have made accurate, fast and robust measurement of animal behavior a reality. In the past years powerful tools specifically designed to aid the measurement of behavior have come to fruition. Here we discuss how capturing ...

2020

The ability to control a behavioral task or stimulate neural activity based on animal behavior in real-time is an important tool for experimental neuroscientists. Ideally, such tools are noninvasive, low-latency, and provide interfaces to trigger external ...

2020