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Alexander Mathis

Related publications (40)

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Using DeepLabCut for 3D markerless pose estimation across species and behaviors

Alexander Mathis, Mackenzie Mathis, Matthias Bethge, Tanmay Nath, An Chi Chen

Noninvasive behavioral tracking of animals during experiments is critical to many scientific pursuits. Extracting the poses of animals without using markers is often essential to measuring behavioral effects in biomechanics, genetics, ethology, and neurosc ...

2019

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Deep neural networks are highly effective tools for human and animal pose estimation. However, robustness to out-of-domain data remains a challenge. Here, we probe the transfer and generalization ability for pose estimation with two architecture classes (M ...

2019

Using DeepLabCut for 3D markerless pose estimation across species and behaviors

Alexander Mathis, Mackenzie Mathis, Matthias Bethge, Tanmay Nath, An Chi Chen

Noninvasive behavioral tracking of animals during experiments is crucial to many scientific pursuits. Extracting the poses of animals without using markers is often essential for measuring behavioral effects in biomechanics, genetics, ethology & neuroscien ...

Neuroscience2018

Towards goal-driven deep neural network models to elucidate human arm proprioception

Alexander Mathis, Matthias Bethge, Pranav Mamidanna

Proprioceptive signals are a critical component of our ability to perform complex movements, identify our posture and adapt to environmental changes. Our movements are generated by a large number of muscles and are sensed via a myriad of different receptor ...

2018

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Quantifying behavior is crucial for many applications in neuroscience. Videography provides easy methods for the observation and recording of animal behavior in diverse settings, yet extracting particular aspects of a behavior for further analysis can be h ...

2018

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2018

On the inference speed and video-compression robustness of DeepLabCut

Alexander Mathis

Pose estimation is crucial for many applications in neuroscience, biomechanics, genetics and beyond. We recently presented a highly efficient method for markerless pose estimation based on transfer learning with deep neural networks called DeepLabCut. Curr ...

Animal Behavior and Cognition2018

The medial amygdala (MeA) plays a critical role in processing species- and sex-specific signals that trigger social and defensive behaviors. However, the principles by which this deep brain structure encodes social information is poorly understood. We used ...

2017

Periodic population codes: From a single circular variable to higher dimensions, multiple nested scales, and conceptual spaces

Alexander Mathis

Across the nervous system, neurons often encode circular stimuli using tuning curves that are not sine or cosine functions, but that belong to the richer class of von Mises functions, which are periodic variants of Gaussians. For a population of neurons en ...

2017

Our motor outputs are constantly re-calibrated to adapt to systematic perturbations. This motor adaptation is thought to depend on the ability to form a memory of a systematic perturbation, often called an internal model. However, the mechanisms underlying ...

2017