Intrathecal implants of bovine chromaffin cells alleviate mechanical allodynia in a rat model of neuropathic pain
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Degradable polymer nanoparticles (NPs, 50nm) based on polypropylene sulfide (PPS) were conjugated to thiolated antigen and adjuvant proteins by reversible disulfide bonds and evaluated in mucosal vaccination. Ovalbumin was used as a model antigen, and anti ...
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The chromosomal locus encoding the early secreted antigenic target, 6 kDa (ESAT-6) secretion system 1 of Mycobacterium tuberculosis, also referred to as "region of difference 1 (RD1)," is absent from Mycobacterium bovis bacillus Calmette-Guerin (BCG). In t ...
[...] Low back pain affects nearly 80% the population at least once in their lifetime. Intervertebral disc (IVD) degeneration is thought to play a role in the development and onset of low back pain. The center part of the disc, the nucleus pulposus (NP), w ...
Objective: Several cell carriers need to be selected and characterized for their compatibility with fetal cartilaginous cell survival and activity. In order to assess the in vivo regeneration capacity of fetal cartilaginous cells, these cell carriers will ...
T lymphocytes (T cells) are key components of the adaptive immune system. These cells are able to recognize an enormous variety of pathogens thanks to the great specificity of their trans-membrane proteins, the T cell receptors (TCRs). TCR diversity is cre ...
Computational methods have been developped to simulate the complex interactions between components of the immune system. Chao introduced a method based on a stage structured approach to studying the Cytotoxic T cells response to an infection. In this work, ...
The objective of this study was to objectively assess the physical activity of daily living in chronic pain patients treated with spinal cord stimulation (SCS). Changes in pain and spontaneous physical activity following SCS were evaluated under real life ...
The protooncogene MYC has been implicated in both the proliferation and programmed cell death of lymphoid cells, and in the genesis of lymphoid tumors. Here, we report that overexpression of MYC, as found in many lymphomas, can break immune tolerance. Mice ...
