Important design issues of a high efficiency cyclotron complex to drive the Energy Amplifier
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The interaction between oxaliplatin and the model protein ubiquitin (Ub) was investigated in a top-down approach by means of high-resolution electrospray ionization mass spectrometry (ESI-MS) using diverse tandem mass spectrometric (MS/MS) techniques, incl ...
The strong space charge regime of future operation of CERN's circular particle accelerators is investigated andmitigation strategies are developed in the framework of the present thesis. The intensity upgrade of the injector chain of Large Hadron Collider ...
This thesis presents new superconducting compact (as opposed to separated-sector ) cyclotron designs for injection in CABOTO, a linac developed by the TERA Foundation delivering C6+/H2+ beams up to 400 MeV/u for ion beam therapy. This association of a vari ...
The present invention relates to a method and device for measuring m/z ratios of ions in ion cyclotron resonance (ICR) mass spectrometry. The described ion traps for ICR mass spectrometry are distinct from the previous configurations by having one or many ...
In this chapter, we describe the advances in high-resolution and tandem mass spectrometry applied for structural analysis of complex molecular systems. Focus is made on Fourier transform mass spectrometers (FTMS) because of their ability to routinely provi ...
Recent experimental and theoretical findings suggest that the concept of time-dependent instantaneous frequency(IF) is required to comprehensively describe ion motion and mass spectra generation in Fourier transform mass spectrometry (FTMS). Here, we deriv ...
Double-resonance spectroscopic schemes in combination with cryogenic ion traps are the go-to techniques when isomer-specific high-resolution spectra are required for analysis of molecular ions. Their limitation lies in the requirement for well-resolved, is ...
For a dedicated performance optimization of negative hydrogen ion sources applied at particle accelerators, a detailed assessment of the plasma processes is required. Due to the compact design of these sources, diagnostic access is typically limited to opt ...
Institute of Physics (IoP) and Deutsche Physikalische Gesellschaft2017
Hadron beams - approximately 200 MeV protons and 400 MeV/u fully stripped carbon ions - are better suited to treat deep-seated tumours than X ray beams - produced by electrons accelerated by linear accelerators (linacs) to 5-25 MeV - because they leave the ...
Molecular and macromolecular structure analysis by high resolution and accurate mass spectrometry (MS) is indispensable for a number of fundamental and applied research areas, including health and energy domains. Comprehensive structure analysis of molecul ...