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Coherent x-ray scattering

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Phase Reconstruction of Low-Energy Electron Holograms of Individual Proteins

Klaus Kern, Stephan Rauschenbach, Sven Alexander Szilagyi, Hannah Julia Ochner

Low-energy electron holography (LEEH) is one of the few techniques capable of imaging large and complex three-dimensional molecules, such as proteins, on the single molecule level at subnanometer resolution. During the imaging process, the structural infor ...

AMER CHEMICAL SOC2022

Lock-in incoherent differential phase contrast imaging

Christophe Moser, Timothé Laforest, Damien Claude-Marie Loterie, Chiara Bonati

We introduce a lock-in method to increase the phase contrast in incoherent differential phase contrast (DPC) imaging. This method improves the phase sensitivity by the analog removal of the background. The use of a smart pixel detector with in-pixel signal ...

CHINESE LASER PRESS2022

3D reconstruction of weakly scattering objects from 2D intensity-only measurements using the Wolf transform

Demetri Psaltis, Joowon Lim, Elizabeth Elena Antoine, Ahmed Ayoub

A new approach to optical diffraction tomography (ODT) based on intensity measurements is presented. By applying the Wolf transform directly to intensity measurements, we observed unexpected behavior in the 3D reconstruction of the sample. Such a reconstru ...

OPTICAL SOC AMER2021

Imaging with Coherent X-rays: From the Early Synchrotron Tests to SYNAPSE

Giorgio Margaritondo

The high longitudinal and lateral coherence of synchrotron X-rays sources radically transformed radiography. Before them, the image contrast was almost only based on absorption. Coherent synchrotron sources transformed radiography into a multi-faceted tool ...

MDPI2021

Stochasticity helps to navigate rough landscapes: comparing gradient-descent-based algorithms in the phase retrieval problem

Lenka Zdeborová, Francesca Mignacco

In this paper we investigate how gradient-based algorithms such as gradient descent (GD), (multi-pass) stochastic GD, its persistent variant, and the Langevin algorithm navigate non-convex loss-landscapes and which of them is able to reach the best general ...

IOP PUBLISHING LTD2021

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Characterizing and controlling the uniformity of nanoparticles is crucial for their application in science and technology because crystalline defects in the nanoparticles strongly affect their unique properties. Recently, ultra-short and ultra-bright X-ray ...

INT UNION CRYSTALLOGRAPHY2020

Diffractive Optical Elements Investigation in the Phase Domain

Toralf Scharf, Myun Sik Kim, Dong Cheon Kim, Michail Symeonidis

In this work we demonstrate the advantages of investigating diffractive optical elements in the phase domain. In this regime we can detect features that are not restrained by the diffraction limit and relate them to the geometrical and optical properties o ...

SPIE-INT SOC OPTICAL ENGINEERING2019

Here we present a new approach to diffraction imaging of amyloid fibrils, combining a freestanding graphene support and single nanofocused X-ray pulses of femtosecond duration from an X-ray free-electron laser. Due to the very low background scattering fro ...

Springer Science and Business Media LLC2018

Holographic device or imager

Christophe Moser, Manon Rostykus

The present disclosure concerns a holographic system or device comprising at least one optical guiding element (100) configured to redirect light incident from a light source (101) to a target interference plane (103), wherein the optical guiding element i ...

2018

Coherent imaging from bacteria to multicellular organisms

Séverine Coquoz

Structural and functional imaging of cells, tissues and organisms is crucial for understanding biomedical processes. Fluorescence microscopy is an established tool and has contributed to many discoveries in the life sciences. This technique provides molecu ...

EPFL2017