Publication
Salt restriction induces pseudohypoaldosteronism type 1 in mice expressing low levels of the beta-subunit of the amiloride-sensitive epithelial sodium channel
Related publications (35)
A mouse model for the renal salt-wasting syndrome pseudohypoaldosteronism
Aldosterone-dependent epithelial sodium transport in the distal nephron is mediated by the absorption of sodium through the highly selective, amiloride-sensitive epithelial sodium channel (ENaC) made of three homologous subunits (alpha, beta, and gamma). I ...
1997Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice
The amiloride-sensitive epithelial sodium channel, ENaC, is a heteromultimeric protein made up of three homologous subunits (alpha, beta and gamma) (1,2). In vitro, assembly and expression of functional active sodium channels in the Xenopus oocyte is stric ...
1996Contributions of vascular tone and structure to elastic properties of a medium-sized artery
Isobaric compliance and distensibility of the radial artery were recently reported to be normal or slightly increased in untreated hypertensive patients. However, these findings provide no information on the intrinsic mechanical properties of the wall mate ...
1996Theoretical study of dynamics of arterial wall remodeling in response to changes in blood pressure
Nikolaos Stergiopoulos, Alexander Rachev
The dynamics of arterial wall remodeling was studied on the basis of a phenomenological mathematical model. Sustained hypertension was simulated by a step increase in blood pressure. Remodeling rate equations were postulated for the evolution of the geomet ...
1996Non-invasive determination of arterial diameter and distensibility by echo-tracking techniques in hypertension
METHODOLOGY: A new non-invasive ultrasonic device was developed to characterize the biomechanical properties of medium and large peripheral arteries. Simultaneous recordings of internal diameter and blood pressure over the whole cardiac cycle are used to e ...
1992