Interneuron Diversity series: Molecular and genetic tools to study GABAergic interneuron diversity and function
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The terrorist attacks of September 11, 2001 raised major concerns about the vulnerability of global transportation systems to transnational crime and terrorism. Although the attacks occurred in the context of passenger transport, they spurred unprecedented ...
The pedunculopontine tegmental (PPT) nucleus has long been implicated in the regulation of cortical activity and behavioral states, including rapid eye-movement (REM) sleep. For example, electrical stimulation of the PPT region during sleep leads to rapid ...
ICT-Enabled Social Innovation can help making existing service more efficient and effective, but also produce new services as a result of integration among different policy silos. Information and Communication Technologies (ICTs) can also promote conceptua ...
GABAergic neurons are a minor fraction of the neocortical neuronal population, but they are highly diverse in their features. The GABAergic neurons can be divided into three largely non-overlapping groups, defined through the expression of ionotropic serot ...
Intracellular recordings of membrane potential in vitro have defined fundamental properties of synaptic communication. Much less is known about the properties of synaptic connectivity and synaptic transmission in vivo. Here, we combined single-cell opto-ge ...
There is compelling evidence that glutamate can act as a cotransmitter in the mammalian brain. Interestingly, the third vesicular glutamate transporter (VGLUT3) is primarily found in neurons that were anticipated to be nonglutamatergic. Whereas the functio ...
2015
Classical peer review has been subject to intense criticism for slowing down the publication process, bias against specific categories of paper and author, unreliability, inability to detect errors and fraud, unethical practices, and the lack of recognitio ...
A deeper understanding of post-stroke plasticity is critical to devise more effective pharmacological and rehabilitative treatments. The GABAergic system is one of the key modulators of neuronal plasticity, and plays an important role in the control of "cr ...
ICT-Enabled Social Innovation can help making existing service more efficient and effective, but also produce new services as a result of integration among different policy silos. Information and Communication Technologies (ICTs) can also promote conceptua ...
Sensory processing in neocortex is primarily driven by glutamatergic excitation, which is counterbalanced by GABAergic inhibition, mediated by a diversity of largely local inhibitory interneurons. Here, we trained mice to lick a reward spout in response to ...