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NEOBASE: databasing the neocortical microcircuit

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Motor Control in the Mouse Whisker System

Varun Sreenivasan

The motor systems of the mammalian brain are a remarkable product of many millions of years of evolution. It is the motor systems that make us and other mammals mobile, that guide our actions in response to sensory information and conversely modulate the v ...

EPFL2015

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As data collections become larger and larger, users are faced with increasing bottlenecks in their data analysis. More data means more time to prepare and to load the data into the database before executing the desired queries. Many applications already av ...

Assoc Computing Machinery2015

Task-Driven Activity Reduces the Cortical Activity Space of the Brain: Experiment and Whole-Brain Modeling

Patric Hagmann

How a stimulus or a task alters the spontaneous dynamics of the brain remains a fundamental open question in neuroscience. One of the most robust hallmarks of task/stimulus-driven brain dynamics is the decrease of variability with respect to the spontaneou ...

Public Library Science2015

High Bandwidth Synaptic Communication and Frequency Tracking in Human Neocortex

Michele Giugliano

Neuronal firing, synaptic transmission, and its plasticity form the building blocks for processing and storage of information in the brain. It is unknown whether adult human synapses are more efficient in transferring information between neurons than roden ...

Public Library Science2014

The neocortex is the most distinctive feature of the mammalian brain and it is considered to be the substrate of high-order cognitive functions. The nature and the arrangement of the diverse neuronal elements constituting its multiple areas have received l ...

EPFL2014

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The lack of a common benchmark for the evaluation of the gaze estimation task from RGB and RGB-D data is a serious limitation for distinguishing the advantages and disadvantages of the many proposed algorithms found in the literature. The EYEDIAP database ...

Idiap2014

The paper discusses the concept of value of integration in two apparently distant research domains, database and service domains. In the area of virtual database integration, we address the problem of increased utility in an organization resulting from ado ...

IEEE2014

Learning Object-level Impedance Control for Robust Grasping and Dexterous Manipulation

Aude Billard, Hang Yin, Miao Li, Kenji Tahara

Object-level impedance control is of great importance for object-centric tasks, such as robust grasping and dexterous manipulation. Despite the recent progress on this topic, how to specify the desired object impedance for a given task remains an open issu ...

2014

Fifteen years SIB Swiss Institute of Bioinformatics: life science databases, tools and support

Jacques Rougemont, Philipp Bucher, Mauro Delorenzi, Heinz Stockinger, Ioannis Xenarios, Olivier Michielin, Amos Bairoch

The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) was created in 1998 as an institution to foster excellence in bioinformatics. It is renowned worldwide for its databases and software tools, such as UniProtKB/Swiss-Prot, PROSITE, SWISS-MODEL, STRI ...

Oxford University Press2014

Synaptic Computation and Sensory Processing in Neocortical Layer 2/3

Carl Petersen, Sylvain Crochet

Computations in neocortical circuits are predominantly driven by synaptic integration of excitatory glutamatergic and inhibitory GABAergic inputs. New optical, electrophysiological, and genetic methods allow detailed in vivo investigation of the superficia ...

Cell Press2013