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Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease

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Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease

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A fluorescent multi-domain protein reveals the unfolding mechanism of Hsp70

An integrative approach to elucidate the mechanisms and dynamics of Huntingtin aggregation and inclusion formation in neuronal models of Huntington's Disease

Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the UPR in models of neurodegeneration

A New Chemoenzymatic Semisynthetic Approach Provides Insight into the Role of Phosphorylation beyond Exon1 of Huntingtin and Reveals N-Terminal Fragment Length-Dependent Distinct Mechanisms of Aggregation

Molecular dissection of amyloid disaggregation by human HSP70

Ultrasensitive quantitative measurement of huntingtin phosphorylation at residue S13

Development of novel methods and tools to decipher the huntingtin post-translation modifications code

The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain

Application of anti-amyloid beta immunization using encapsulated cell technology in mouse models of Alzheimer's disease

Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy