Memory pagingIn computer operating systems, memory paging (or swapping on some Unix-like systems) is a memory management scheme by which a computer stores and retrieves data from secondary storage for use in main memory. In this scheme, the operating system retrieves data from secondary storage in same-size blocks called pages. Paging is an important part of virtual memory implementations in modern operating systems, using secondary storage to let programs exceed the size of available physical memory.
Spectre (security vulnerability)Spectre refers to one of the two original transient execution CPU vulnerabilities (the other being Meltdown), which involve microarchitectural timing side-channel attacks. These affect modern microprocessors that perform branch prediction and other forms of speculation. On most processors, the speculative execution resulting from a branch misprediction may leave observable side effects that may reveal private data to attackers.
MicrocodeIn processor design, microcode serves as an intermediary layer situated between the central processing unit (CPU) hardware and the programmer-visible instruction set architecture of a computer. It consists of a set of hardware-level instructions that implement higher-level machine code instructions or control internal finite-state machine sequencing in many digital processing components. While microcode is utilized in general-purpose CPUs in contemporary desktops, it also functions as a fallback path for scenarios that the faster hardwired control unit is unable to manage.
Computer simulationComputer simulation is the process of mathematical modelling, performed on a computer, which is designed to predict the behaviour of, or the outcome of, a real-world or physical system. The reliability of some mathematical models can be determined by comparing their results to the real-world outcomes they aim to predict. Computer simulations have become a useful tool for the mathematical modeling of many natural systems in physics (computational physics), astrophysics, climatology, chemistry, biology and manufacturing, as well as human systems in economics, psychology, social science, health care and engineering.
Stem cellIn multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type.
Cell growthCell growth refers to an increase in the total mass of a cell, including both cytoplasmic, nuclear and organelle volume. Cell growth occurs when the overall rate of cellular biosynthesis (production of biomolecules or anabolism) is greater than the overall rate of cellular degradation (the destruction of biomolecules via the proteasome, lysosome or autophagy, or catabolism). Cell growth is not to be confused with cell division or the cell cycle, which are distinct processes that can occur alongside cell growth during the process of cell proliferation, where a cell, known as the mother cell, grows and divides to produce two daughter cells.
Cell signalingIn biology, cell signaling (cell signalling in British English) or cell communication is the ability of a cell to receive, process, and transmit signals with its environment and with itself. Cell signaling is a fundamental property of all cellular life in prokaryotes and eukaryotes. Signals that originate from outside a cell (or extracellular signals) can be physical agents like mechanical pressure, voltage, temperature, light, or chemical signals (e.g., small molecules, peptides, or gas).
T helper cellThe T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune system. They aid the activity of other immune cells by releasing cytokines. They are considered essential in B cell antibody class switching, breaking cross-tolerance in dendritic cells, in the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages and neutrophils.
Non-uniform memory accessNon-uniform memory access (NUMA) is a computer memory design used in multiprocessing, where the memory access time depends on the memory location relative to the processor. Under NUMA, a processor can access its own local memory faster than non-local memory (memory local to another processor or memory shared between processors). The benefits of NUMA are limited to particular workloads, notably on servers where the data is often associated strongly with certain tasks or users.
Cache pollutionCache pollution describes situations where an executing computer program loads data into CPU cache unnecessarily, thus causing other useful data to be evicted from the cache into lower levels of the memory hierarchy, degrading performance. For example, in a multi-core processor, one core may replace the blocks fetched by other cores into shared cache, or prefetched blocks may replace demand-fetched blocks from the cache. Consider the following illustration: T[0] = T[0] + 1; for i in 0..
