Publications related to Prevention or treatment of type 2 diabetes or cardiovascular disease with ppar modulators

Semantic representation and processing of hypoglycemic events derived from wearable sensor data

Karl Aberer, Jean Paul Calbimonte Perez, Jean-Eudes Marie Ranvier

Diabetes Type 1 is a metabolic disease which results in a lack of insulin production, causing high glucose levels in the blood. It is crucial for diabetic patients to balance this glucose level, and they depend on external substances to do so. In order to ...

Ios Press2017

Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging

Theo Lasser, Anne Grapin-Botton, Martin Villiger, Arno Pino Bouwens, Daniel Pawel Szlag, Corinne Berclaz, Jérôme Extermann, Joan Goulley

Aims/hypothesis It is generally accepted that structural and functional quantitative imaging of individual islets would be beneficial to elucidate the pathogenesis of type 1 diabetes. We here introduce functional optical coherence imaging (FOCI) for fast, ...

Springer Verlag2016

Comparative Performance of Different Nanostructured Electrochemical Sensors on Insulin Detection

Giovanni De Micheli, Sandro Carrara, Lucia Grassi

New advancements in the management of type I diabetic patients (T1DM) call for a new generation of monitoring systems based upon an array of metabolic biosensors including sensors for insulin detection. Blood insulin values are always less than 270 pM; the ...

2013

The gait and balance of patients with diabetes can be improved: a randomised controlled trial

Kamiar Aminian, Stéphane Armand

Gait characteristics and balance are altered in diabetic patients. Little is known about possible treatment strategies. This study evaluates the effect of a specific training programme on gait and balance of diabetic patients. ...

2010

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

László Forró, Aleksandra Radenovic, Andras Kis

Strong epidemiologic evidence suggests an association between Alzheimer disease (AD) and type 2 diabetes. To determine if amyloid beta (A

\beta

) and hyperphosphorylated tau occurs in type 2 diabetes, pancreas tissues from 21 autopsy cases (10 type 2 diabe ...

Elsevier2010

An exercise intervention to improve diabetic patients' gait in a real-life environment

Kamiar Aminian, Stéphane Armand

Aims: Gait characteristics and balance are altered in diabetic individuals. Little is known about possible treatment strategies. This study evaluated the effect of a specific training program on diabetic patients' gait. ...

Elsevier2010

Brain glucose concentrations in poorly controlled diabetes mellitus as measured by high-field magnetic resonance spectroscopy

Rolf Gruetter

Hyperglycemia and diabetes alter the function and metabolism of many tissues. The effect on the brain remains poorly defined, but some animal data suggest that chronic hyperglycemia reduces rates of brain glucose transport and/or metabolism. To address thi ...

Elsevier2005

Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology

Johan Auwerx

The peroxisome proliferator-activated receptor gamma (PPARgamma) is a prototypical member of the nuclear receptor superfamily and integrates the control of energy, lipid, and glucose homeostasis. PPARgamma can bind a variety of small lipophilic compounds d ...

2004

Nuclear receptors and the control of metabolism

Johan Auwerx

The metabolic nuclear receptors act as metabolic and toxicological sensors, enabling the organism to quickly adapt to environmental changes by inducing the appropriate metabolic genes and pathways. Ligands for these metabolic receptors are compounds from d ...

2003

Isolation and Characterization of Human Monoclonal Autoantibodies to Glutamic Acid Decarboxylase

Steinunn Baekkeskov Hanahan

Production of human monoclonal autoantibodies to glutamic acid decarboxylase Mr 65,000 (GAD65), characterization of their isotype, binding affinity, V region sequences and competition with autoantibodies in patients' sera is described. Lymphocytes from a p ...

Taylor & Francis2002

Prevention or treatment of type 2 diabetes or cardiovascular disease with ppar modulators

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Semantic representation and processing of hypoglycemic events derived from wearable sensor data

Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging

Comparative Performance of Different Nanostructured Electrochemical Sensors on Insulin Detection

The gait and balance of patients with diabetes can be improved: a randomised controlled trial

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

An exercise intervention to improve diabetic patients' gait in a real-life environment

Brain glucose concentrations in poorly controlled diabetes mellitus as measured by high-field magnetic resonance spectroscopy

Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology

Nuclear receptors and the control of metabolism

Isolation and Characterization of Human Monoclonal Autoantibodies to Glutamic Acid Decarboxylase

Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging

An exercise intervention to improve diabetic patients' gait in a real-life environment

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

Semantic representation and processing of hypoglycemic events derived from wearable sensor data

Comparative Performance of Different Nanostructured Electrochemical Sensors on Insulin Detection

The gait and balance of patients with diabetes can be improved: a randomised controlled trial

Brain glucose concentrations in poorly controlled diabetes mellitus as measured by high-field magnetic resonance spectroscopy

Nuclear receptors and the control of metabolism

Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology

Isolation and Characterization of Human Monoclonal Autoantibodies to Glutamic Acid Decarboxylase