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The possibility to use information from cortical neurons to drive neuroprosthetic devices is an area that has recently garnered a lot of attention within neuroscience. Most of this research has been directed towards restoring upper limb motility. In this s ...
Viral vectors injected into the mouse brain offer the possibility for localized genetic modifications in a highly controlled manner. Lentivector injection into mouse neocortex transduces cells within a diameter of approximately 200mum, which closely matche ...
How well are single-cell properties reproduced by the present-day neuronal models? Recently, several labs have approached this question by assessing the quality of the models with respect to spike timing prediction or characteristic features of the voltage ...
The tactile somatosensory pathway from whisker to cortex in rodents provides a well-defined system for exploring the link between molecular mechanisms, synaptic circuits, and behavior. The primary somatosensory cortex has an exquisite somatotopic map where ...
Facial expression and direction of gaze are two important sources of social information, and what message each conveys may ultimately depend on how the respective information interacts in the eye of the perceiver. Direct gaze signals an interaction with th ...
Whether signals from different sensory modalities converge and interact within primary cortices in humans is unresolved, despite emerging evidence in animals. This is partially because of debates concerning the appropriate analyses of functional magnetic r ...
We review here the development of Hodgkin-Huxley (HH) type models of cerebral cortex and thalamic neurons for network simulations. The intrinsic electrophysiological properties of cortical neurons were analyzed from several preparations, and we selected th ...
The high complexity of cortical convolutions in humans remains a mystery for both engineers to measure and compare it, and for biologists to understand it. We developed a method for the quantification of the cortical area allowed by the process of folding. ...
Tactile information is actively acquired and processed in the brain through concerted interactions between movement and sensation. Somatosensory input is often the result of self-generated movement during the active touch of objects, and conversely, sensor ...
The most general and striking evidence related with brain injury is that of the restoration of function. Recovery of motor and somatosensory functions has shown to commonly occur after stroke, but not all individuals show improvement. Clinical studies have ...