Confocal microscopyConfocal microscopy, most frequently confocal laser scanning microscopy (CLSM) or laser scanning confocal microscopy (LSCM), is an optical imaging technique for increasing optical resolution and contrast of a micrograph by means of using a spatial pinhole to block out-of-focus light in image formation. Capturing multiple two-dimensional images at different depths in a sample enables the reconstruction of three-dimensional structures (a process known as optical sectioning) within an object.
Optical telescopeAn optical telescope is a telescope that gathers and focuses light mainly from the visible part of the electromagnetic spectrum, to create a magnified image for direct visual inspection, to make a photograph, or to collect data through electronic s. There are three primary types of optical telescope: Refracting telescopes, which use lenses and less commonly also prisms (dioptrics) Reflecting telescopes, which use mirrors (catoptrics) Catadioptric telescopes, which combine lenses and mirrors An optical telescope's ability to resolve small details is directly related to the diameter (or aperture) of its objective (the primary lens or mirror that collects and focuses the light), and its light-gathering power is related to the area of the objective.
Fluorescence microscopeA fluorescence microscope is an optical microscope that uses fluorescence instead of, or in addition to, scattering, reflection, and attenuation or absorption, to study the properties of organic or inorganic substances. "Fluorescence microscope" refers to any microscope that uses fluorescence to generate an image, whether it is a simple set up like an epifluorescence microscope or a more complicated design such as a confocal microscope, which uses optical sectioning to get better resolution of the fluorescence image.
Fresnel lensA Fresnel lens ('freinɛl,-nəl ; 'frɛnɛl,-əl ; or freɪˈnɛl ) is a type of composite compact lens which reduces the amount of material required compared to a conventional lens by dividing the lens into a set of concentric annular sections. The simpler dioptric (purely refractive) form of the lens was first proposed by Georges-Louis Leclerc, Comte de Buffon, and independently reinvented by the French physicist Augustin-Jean Fresnel (1788–1827) for use in lighthouses.
Theoretical physicsTheoretical physics is a branch of physics that employs mathematical models and abstractions of physical objects and systems to rationalize, explain and predict natural phenomena. This is in contrast to experimental physics, which uses experimental tools to probe these phenomena. The advancement of science generally depends on the interplay between experimental studies and theory. In some cases, theoretical physics adheres to standards of mathematical rigour while giving little weight to experiments and observations.
EvaluationIn common usage, evaluation is a systematic determination and assessment of a subject's merit, worth and significance, using criteria governed by a set of standards. It can assist an organization, program, design, project or any other intervention or initiative to assess any aim, realisable concept/proposal, or any alternative, to help in decision-making; or to ascertain the degree of achievement or value in regard to the aim and objectives and results of any such action that has been completed.
Physics beyond the Standard ModelPhysics beyond the Standard Model (BSM) refers to the theoretical developments needed to explain the deficiencies of the Standard Model, such as the inability to explain the fundamental parameters of the standard model, the strong CP problem, neutrino oscillations, matter–antimatter asymmetry, and the nature of dark matter and dark energy. Another problem lies within the mathematical framework of the Standard Model itself: the Standard Model is inconsistent with that of general relativity, and one or both theories break down under certain conditions, such as spacetime singularities like the Big Bang and black hole event horizons.
Standard ModelThe Standard Model of particle physics is the theory describing three of the four known fundamental forces (electromagnetic, weak and strong interactions – excluding gravity) in the universe and classifying all known elementary particles. It was developed in stages throughout the latter half of the 20th century, through the work of many scientists worldwide, with the current formulation being finalized in the mid-1970s upon experimental confirmation of the existence of quarks.
Holographic principleThe holographic principle is a property of string theories and a supposed property of quantum gravity that states that the description of a volume of space can be thought of as encoded on a lower-dimensional boundary to the region — such as a light-like boundary like a gravitational horizon. First proposed by Gerard 't Hooft, it was given a precise string-theory interpretation by Leonard Susskind, who combined his ideas with previous ones of 't Hooft and Charles Thorn.
Impact evaluationImpact evaluation assesses the changes that can be attributed to a particular intervention, such as a project, program or policy, both the intended ones, as well as ideally the unintended ones. In contrast to outcome monitoring, which examines whether targets have been achieved, impact evaluation is structured to answer the question: how would outcomes such as participants' well-being have changed if the intervention had not been undertaken? This involves counterfactual analysis, that is, "a comparison between what actually happened and what would have happened in the absence of the intervention.
