Publications related to Short-term immunosuppression reduces fibrotic cellular infiltration around barium-M-alginate microbeads injected intraportally

Role of BMP signalling in the developing pancreas

The pancreas is an organ of endodermal origin. It is composed of two different tissues; exocrine (acini and ducts) and endocrine (islet of Langerhans). The Bone Morphogenetic Proteins (BMP) are secreted growth factors from the TGFβ superfamily. These prote ...

2008

Tissue engineering complex and mechanically active microenvironments for studies in asthma and cancer

Alice Anna Tomei

The goals of tissue engineering include recapitulating specific tissue functions for regenerative medicine and developing in vitro models of human tissues to study human physiology and pathophysiology and for testing and screening drugs before expensive cl ...

EPFL2008

Real Time Analyses of Myogenesis in Behaving Myoblasts

Loïc Jacot-Descombes

Effective Tissue engineering ultimately depends on understanding the interplay between the proliferation and differentiation stages of development. One of the best systems to examine these processes is myogenesis. Activated myoblasts first undergo many rou ...

2007

Real Time Analysis of Myogenesis in Behaving Myoblasts

Loïc Jacot-Descombes

Effective Tissue engineering ultimately depends on understanding the interplay between the proliferation and differentiation stages of development. One of the best systems to examine these processes is myogenesis. Activated myoblasts first undergo many rou ...

2007

Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types

Friedrich Beermann, Anne Grapin-Botton

All pancreatic endocrine cells, producing glucagon, insulin, somatostatin, or PP, differentiate from Pdx1+ progenitors that transiently express Neurogenin3. To understand whether the competence of pancreatic progenitors changes over time, we generated tran ...

2007

A Polyoxyethylene-Substituted Bimetallic Europium Helicate for Luminescent Staining of Living Cells

Jean-Claude Bünzli, Anne-Sophie Chauvin, Caroline Vandevyver, Bo Song, Steve Comby

The homoditopic ligand

H_2L^{C3}

has been designed to form neutral triple-stranded bimetallic helicates of overall composition [

Ln_2(L^{C3})_3

]. The grafting of the polyoxyethylene fragments ensures water solubility and also favors cell penetration whi ...

2007

Effects of extracellular fiber architecture on cell membrane shear stress in a 3D fibrous matrix

Melody Swartz, Federica Boschetti

Interstitial fluid flow has been shown to affect the organization and behavior of cells in 3D environments in vivo and in vitro, yet the forces driving such responses are not clear. Due to the complex architecture of the extracellular matrix (ECM) and the ...

2007

Mechanobiology in the third dimension

Melody Swartz

Cells are mechanically coupled to their extracellular environments, which play critical roles in both communicating the state of the mechanical environment to the cell as well as in mediating cellular response to a variety of stimuli. Along with the molecu ...

Kluwer Academic Publishers, Springer2005

Synergy between interstitial flow and VEGF directs capillary morphogenesis in vitro through a gradient amplification mechanism

Melody Swartz, Federica Boschetti, Mark Fleury

Cell organization is largely orchestrated by extracellular gradients of morphogenetic proteins. VEGF, an essential factor for capillary formation, is stored in the extracellular matrix, but the mechanisms by which it and other matrix-bound morphogens are m ...

2005

Investigating cellular signaling reactions in single attoliter vesicles

Horst Vogel, Rudolf Hovius, Horst Pick, Erwin Ilegems

Understanding cellular signaling mediated by cell surface receptors is key to modern biomedical research and drug development. The discovery of a growing no. of potential mol. targets and therapeutic compds. requires downscaling and accelerated functional ...

2005

Short-term immunosuppression reduces fibrotic cellular infiltration around barium-M-alginate microbeads injected intraportally

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Role of BMP signalling in the developing pancreas

Tissue engineering complex and mechanically active microenvironments for studies in asthma and cancer

Real Time Analyses of Myogenesis in Behaving Myoblasts

Real Time Analysis of Myogenesis in Behaving Myoblasts

Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types

A Polyoxyethylene-Substituted Bimetallic Europium Helicate for Luminescent Staining of Living Cells

Effects of extracellular fiber architecture on cell membrane shear stress in a 3D fibrous matrix

Mechanobiology in the third dimension

Synergy between interstitial flow and VEGF directs capillary morphogenesis in vitro through a gradient amplification mechanism

Investigating cellular signaling reactions in single attoliter vesicles

Real Time Analyses of Myogenesis in Behaving Myoblasts

Role of BMP signalling in the developing pancreas

Investigating cellular signaling reactions in single attoliter vesicles

Real Time Analysis of Myogenesis in Behaving Myoblasts

Effects of extracellular fiber architecture on cell membrane shear stress in a 3D fibrous matrix

Tissue engineering complex and mechanically active microenvironments for studies in asthma and cancer

A Polyoxyethylene-Substituted Bimetallic Europium Helicate for Luminescent Staining of Living Cells

Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types

Mechanobiology in the third dimension

Synergy between interstitial flow and VEGF directs capillary morphogenesis in vitro through a gradient amplification mechanism