Reconstructing the segmentation network in real space
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Hox genes are central to the specification of structures along the anterior-posterior body axis, and modifications in their expression have paralleled the emergence of diversity in vertebrate body plans. Here we describe the genomic organization of Hox clu ...
Hox genes control many aspects of embryonic development in metazoans. Previous analyses of this gene family has revealed a surprising diversity in terms of gene number and organization between various animal species. In vertebrates, Hox genes are grouped i ...
We observe light localization in a two-dimensional geometry, induced by residual disorder at a photonic band edge located below the light cone. The combination of a spectrally selective illumination and a grating assisted k-space imaging technique allows u ...
Segmentation of paraxial mesoderm in vertebrates is regulated by a genetic oscillator that manifests as a series of wavelike or cyclic gene expression domains in the embryo. In zebrafish, this oscillator involves members of the Delta/Notch intercellular si ...
We report evidence for a mechanism for the maintenance of long-range conserved synteny across vertebrate genomes. We found the largest mammal-teleost conserved chromosomal segments to be spanned by highly conserved noncoding elements (HCNEs), their develop ...
The aim of this paper is to apply a surface parameterization to a blade. This geometric representation should be used as a practical tool in the process of design optimization. Most parameterizations are based on blade section approaches. The parameters ar ...
International Association For Hydraulic Research2004
Since the advent of microarrays, vast amounts of gene expression data have been generated. However, these microarray data fail to reveal the transcription regulatory mechanisms that underlie differential gene expression, because the identity of the respons ...
Finding sequences that control expression of genes is central to understanding genome function. Previous studies have used evolutionary conservation as an indicator of regulatory potential. Here, we present a method for the unbiased in vivo screen of putat ...
We observe light localization in a two-dimensional geometry, induced by residual disorder at a photonic band edge located below the light cone. The combination of a spectrally selective illumination and a grating assisted k-space imaging technique allows u ...
Drosophila germ-band extension (GBE) is an example of the convergence and extension movements that elongate and narrow embryonic tissues. To understand the collective cell behaviours underlying tissue morphogenesis, we have continuously quantified cell int ...