Disposable 600-mL orbitally shaken bioreactor for mammalian cell cultivation in suspension

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A Strategy to Conjugate Bioactive Fragments to Cytotoxic Diiron Bis(cyclopentadienyl) Complexes

Paul Joseph Dyson, Mouna Hadiji, Silvia Schoch, Sarah Alexandra Pais Pereira

A series of bioactive molecules were synthesized from the condensation of aspirin or chlorambucil with terminal alkynes bearing alcohol or amine substituents. Insertion of the resulting alkynes into the iron-carbyne bond of readily accessible diiron bis(cy ...

AMER CHEMICAL SOC2021

Enhancing Algae Biomass Production by Using Dye-Sensitized Solar Cells as Filters

Mohammad Khaja Nazeeruddin, Christian Ludwig, Shivom Sharma, Eya Nicodeme, Peng Qin

One of the most promising options for decreasing the costs of microalgae production is enhancing the production and reducing the energy demand of the culturing systems and the high surface area requirements. Because microalgae growth requires only specific ...

2021

Biotin-NeutrAvidin Mediated Immobilization of Polymer Micro- and Nanoparticles on T Lymphocytes

Harm-Anton Klok, Olivier Burri, Arne Seitz, Romain Guiet, Maxime Ayer

Cells are powerful carriers that can help to improve the delivery of nanomedicines. One approach to use cells as carriers is to immobilize the nanoparticulate cargo on the cell surface. While a plethora of chemical conjugation strategies are available to b ...

2021

The emergence of concentrator photovoltaics for perovskite solar cells

Mohammad Khaja Nazeeruddin, Anurag Roy

The emergence of high-efficiency photovoltaic research is undergoing intense study and is technologically desirable to meet sustainable energy and environmental demand. However, every single solar cell has a theoretical power conversion efficiency limit, a ...

AIP Publishing2021

Carbazol-phenyl-phenothiazine-based sensitizers for dye-sensitized solar cells

Michael Graetzel, Shaik Mohammed Zakeeruddin, Felix Thomas Eickemeyer, Lukas Pfeifer, Wei Huang, Dan Ren, Zhongjin Shen, Yunfei Jiao, Yi Ding

Heteroaromatic units are commonly used as pi-spacers for sensitizers in dye-sensitized solar cells (DSSCs). Here, we investigated the influence of the pi-spacer on the photophysical properties, electrochemical properties and photovoltaic performance of car ...

Royal Society of Chemistry2021

Device and process for tissue-engineering and regenerative medicine

Olaia Maria Naveiras Torres-Quiroga, Thomas Michael Braschler, Amélie Barbara Hildegarde Béduer, Josefine Catharina Pedersen Tratwal, Daniel Naveed Tavakol, Martina Genta

A process and device for direct in-vitro to in-vivo transfer of a living microcarrier culture by controlled dehydration into a viscoelastic material capable of cell-protection during delivery. One particular purpose of the present invention is that of prov ...

2021

Towards an in vitro cardiac model: 3D environment, co-culture, alignment, and mechanical stimulation impact on cell behavior

Fatemeh Navaee

Our aim is to develop a 3D model unit of cardiac muscle: an in-vitro analog of the trabeculae carneae found in vivo. As a base hydrogel matrix for cardiomyocyte culture in 3D, we develop a blend of decellularized extracellular matrix (dECM) and fibrin. Thi ...

EPFL2021

Electrical Losses Mitigation in Silicon Heterojunction Solar Cells

Laurie-Lou Senaud

To overcome the worldwide challenges of climate change, photovoltaics is foreseen to play a significant role in the world electricity production. Nowadays, single junction crystalline silicon (c-Si) based solar cells hold the largest share of the global ph ...

EPFL2021

Spray Synthesis of CuFeO2 Photocathodes and In-Operando Assessment of Charge Carrier Recombination

Kevin Sivula, Nestor Guijarro Carratala, Florian Le Formal, Yongpeng Liu, Florent Alexandre Boudoire, Charles Roger Jean Lhermitte

Semiconducting delafossite-phase CuFeO2 is a promising photocathode material for solar-driven hydrogen production given its suitable energy levels and established robustness for photoelectrochemical water reduction. Nevertheless, reported methods for prepa ...

AMER CHEMICAL SOC2021

Single-cell lipidomics reveals a role for cell-to-cell sphingolipid heterogeneity in fibroblast activation

Laura Capolupo

Cell-to-cell variability plays a key role in tissue patterning by setting initial asymmetry that primes cell fate decisions. Fluctuations in the activity of regulatory molecules can commit individual cells to divergent differentiation pathways, and cell-to ...

EPFL2021

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Towards an in vitro cardiac model: 3D environment, co-culture, alignment, and mechanical stimulation impact on cell behavior

Fatemeh Navaee

EPFL2021